Changes of Functional Status, Symptoms Distress and Quality of Life in Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery

• Conditions: Coronary Artery Bypass Graft Surgery

• Registration Number: NCT01127802
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

The purpose of this study is to explore the changes of functional status, symptoms distress and quality of life in patients undergoing coronary artery bypass graft (CABG) surgery.

Detailed Description

This is an observational cohort study. The participants will be inpatients undergoing elective CABG surgery at one tertiary medical center. Functional status (including activity of daily living, cognitive and nutritional status), symptom distress, and quality of life will be measured at multiple points: pre-surgery, day 1 to 7 post-surgery, before discharge, and 2-4 weeks after discharge. Structured questionnaire will be used to collect demographic and medical characteristics. The Barthel Index, hand-held dynamometer, 6-minute walking test, Mini-Nutritional Assessment (MNA), Mini-Mental State Examination (MMSE), Confusion Assessment Method (CAM), Symptoms Distress Scale, and Short-Form-36 Health Survey (SF-36) will be used to collect functional data and compared for changes. The trajectory of functional status, symptoms distress, and quality of life will be further analyzed. The findings will add to the literature by raising the awareness on changes of functional status, symptoms distress, and quality of life for patients undergoing elective CABG so targeted and timely intervention could be developed and planned.

Study Timeline

• Study Start: 2010-01
• Status Verified: 2010-05
• Study First Submitted: 2010-05-20
• Study First Submitted QC: 2010-05-20
• Last Update Submitted: 2010-05-20
• Study First Posted: 2010-05-21
• Last Update Posted: 2010-05-21
• Primary Completion: 2011-03
• Study Completion: 2011-03

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• receive elective coronary artery bypass surgery
• able to communicate in Chinese and Taiwanese
• walk independently or use walker
• length of stay is over 7 days

Read More

Exclusion Criteria

• unable to walk
• mechanical ventilation
• neural or muscle disease to influence ambulation(ex: Parkinson Disease)
• asthma
• severe psychotic disorder that prevents patient from participating in test

Read More

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified