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Changes in cerebral blood flow and saliva volume induced by near-infrared radiatio

Phase 1
Conditions
Dry mouse, bruxism, periodontal disease, and dementia
Registration Number
JPRN-UMIN000041952
Lead Sponsor
Kanagawa dental university Division of Oral Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
20
Inclusion Criteria

Not provided

Exclusion Criteria

People who are sick or on long-term medication

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Cerebral blood flow and saliva volume will be measured before the study begins. Saliva will be collected using a salivator and resting saliva volume will be measured. Next, the subjects will wear near-infrared spectroscopy (NIRS) and be irradiated with near-infrared radiation for 30 seconds to one minute at a time in eight blocks according to the irradiation manual. The subjects were irradiated with near-infrared light for 30 seconds to one minute at a time, according to the irradiation manual, in eight blocks. The rate of change in the signal at this time was measured by NIRS. As a control, we will measure the change in cerebral blood flow rate of the gingival massage in the same order and at the same time as the experimental group.
Secondary Outcome Measures
NameTimeMethod
ear-infrared irradiation was continued for one week at home after brushing the teeth at night according to the irradiation manual, and saliva was collected again after one week to compare saliva levels.
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