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Clinical Trials/NCT04682548
NCT04682548
Completed
Not Applicable

Estimating Prevalence of COVID-19 Infection and SARS-CoV-2 Antibodies in MS Patients With and Without Ocrelizumab Treatment, and Comparing Immune Responses to COVID-19 in MS Patients on Ocrelizumab and Healthy Controls

NYU Langone Health1 site in 1 country920 target enrollmentJanuary 5, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Multiple Sclerosis
Sponsor
NYU Langone Health
Enrollment
920
Locations
1
Primary Endpoint
Seropositivie Rate Against SARS-CoV-2
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

This non-interventional, biospecimen collection study is designed to help us better understand whether MS patients have impaired immune defenses to COVID-19 infection. The potential influence of immune modulating medications for MS will be considered through these exploratory studies. This study is also designed to provide context for interpretation of anti-SARS CoV2 serologies in MS patients during convalescence from COVID-19 infection.

Registry
clinicaltrials.gov
Start Date
January 5, 2021
End Date
September 15, 2022
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Seropositivie Rate Against SARS-CoV-2

Time Frame: Baseline, Day 0

Seropositivity rate against SARS-CoV-2 (nucleocapsid and/or spike proteins, as available) as measured by the Roche DIA antibody assay in MS patients.

Secondary Outcomes

  • T Cell Response(Baseline, Day 0)

Study Sites (1)

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