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EFFECTIVENESS OF ONE DENTAL PREVENTIVE AGENT OVER ANOTHER IN PREVENTING DENTAL CARIES AMONG THALASSEMIA PATIENTS

Phase 4
Conditions
Health Condition 1: K023- Arrested dental cariesHealth Condition 2: D561- Beta thalassemia
Registration Number
CTRI/2023/11/059838
Lead Sponsor
MATERIAL CONSUMABLE and INFRASTRUCTURE AND INSTITUTIONAL SUPPORT
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. Thalassemia major patients enrolled in institution of Medicine (Hematology), Post graduate

Institute of Medical Sciences, Rohtak, Haryana.

2. Patients aged above 18 years.

3. Thalassemia major patients with Nyvad score, 2 and 3 (active enamel and dentinal caries,

respectively, not close to pulp).

4. Topical SDF and Silver nitrate followed by fluoride varnish will be applied only on

labial/buccal, lingual/palatal & occlusal surfaces of all teeth.

5. At least 20 teeth present excluding 3rd molars or fully dentate patients will be included in study.

6. Patients who have given written consent for the study.

Exclusion Criteria

1. Patients with other systemic disorders like serious or unstable cardiac, renal diseases,

hypertensive, pulmonary, endocrine disorders.

2. Chronic smokers, alcohol or drug abusers.

3. Uncooperative patients and with known silver allergy.

4. Patients with reduced mouth opening.

5. Teeth which are grossly broken, with more than one- third of the crown structure missing

or with pulpal involvement.

6. Presence of an abscess or sinus, obvious discolouration or premature hypermobility.

7. Pregnant women or lactating mothers.

8. Patient under immunosuppressive drugs.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Caries arrest rate , Caries Prevalence , Caries preventive fractionTimepoint: 3 and 6 months
Secondary Outcome Measures
NameTimeMethod
patient satisfaction and acceptabilityTimepoint: 3 and 6 months
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