THRA_hematologic Variables

Completed

• Conditions: Avascular Necrosis of Hip

• Registration Number: NCT01521858
• Lead Sponsor: Seoul National University Bundang Hospital

Brief Summary

Total hip replacement arthroplasty is a surgery having intra- and postoperative substantial blood loss. The investigators will investigate the relationship between the various hematologic variables and postoperative bleeding volume.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2012-01
• Study First Submitted: 2012-01-09
• Study First Submitted QC: 2012-01-26
• Study First Posted: 2012-01-31
• Primary Completion: 2013-02
• Study Completion: 2013-02
• Status Verified: 2013-08
• Last Update Submitted: 2013-08-28
• Last Update Posted: 2013-08-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 73

Inclusion Criteria

• avascular necrosis of hip
• total hip replacement arthroplasty

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Exclusion Criteria

• revision operation
• hematologic disease
• anticoagulant medication
• preoperative hemoglobin < 10 g/dl
• preoperative transfusion of red blood cells

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
fibrinogen concentration	preoperative 1 day and postoperative 1 day
Rotational thromboelastometry	preoperative 1 day and postoperative 1 day
postoperative bleeding volume	at first postoperative day
Hemoglobin	preoperative 1 day and postoperative 1 day
hematocrit	preoperative 1 day and postoperative 1 day
platelet	preoperative 1 day and postoperative 1 day
prothrombin time_international normalized ratio	preoperative 1 day and postoperative 1 day
activated partial prothrombin time	preoperative 1 day and postoperative 1 day

Secondary Outcome Measures

Name	Time	Method
volume of infused fluid during operation	Period from starting to finishing the operation (During operaiton, an expected average of 3 hours)	Infused total crystalloid and colloid volume during the operation will be recorded.
intraoperative urine output	Period from starting to finishing the operation (During operaiton, an expected average of 3 hours)
transfusion units	Period from starting to finishing the operation (During operaiton, an expected average of 3 hours) and postoperative first day	Red blood cell

Trial Locations

Locations (1)

Seoul National University Bundang Hospital; 🇰🇷 Seongnam, Gyounggi, Korea, Republic of