Relations Between Hematologic Variables and Postoperative Bleeding in Total Hip Replacement Arthroplasty
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Avascular Necrosis of Hip
- Sponsor
- Seoul National University Bundang Hospital
- Enrollment
- 73
- Locations
- 1
- Primary Endpoint
- Rotational thromboelastometry
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
Total hip replacement arthroplasty is a surgery having intra- and postoperative substantial blood loss. The investigators will investigate the relationship between the various hematologic variables and postoperative bleeding volume.
Investigators
Hyo-Seok Na
Assistant professor
Seoul National University Bundang Hospital
Eligibility Criteria
Inclusion Criteria
- •avascular necrosis of hip
- •total hip replacement arthroplasty
Exclusion Criteria
- •revision operation
- •hematologic disease
- •anticoagulant medication
- •preoperative hemoglobin \< 10 g/dl
- •preoperative transfusion of red blood cells
Outcomes
Primary Outcomes
Rotational thromboelastometry
Time Frame: preoperative 1 day and postoperative 1 day
postoperative bleeding volume
Time Frame: at first postoperative day
Hemoglobin
Time Frame: preoperative 1 day and postoperative 1 day
hematocrit
Time Frame: preoperative 1 day and postoperative 1 day
activated partial prothrombin time
Time Frame: preoperative 1 day and postoperative 1 day
fibrinogen concentration
Time Frame: preoperative 1 day and postoperative 1 day
platelet
Time Frame: preoperative 1 day and postoperative 1 day
prothrombin time_international normalized ratio
Time Frame: preoperative 1 day and postoperative 1 day
Secondary Outcomes
- volume of infused fluid during operation(Period from starting to finishing the operation (During operaiton, an expected average of 3 hours))
- intraoperative urine output(Period from starting to finishing the operation (During operaiton, an expected average of 3 hours))
- transfusion units(Period from starting to finishing the operation (During operaiton, an expected average of 3 hours) and postoperative first day)