Revision Total Hip Replacement Arthroplasty and Hematologic Variables

Completed

• Conditions: Avascular Necrosis of Hip; Degenerative Hip Joint Disease

• Registration Number: NCT02951741
• Lead Sponsor: Seoul National University Bundang Hospital

Brief Summary

Revision total hip replacement arthroplasty is a surgery having intra- and postoperative substantial blood loss. The investigators will investigate the relationship between the various hematologic variables and postoperative bleeding volume.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-04
• Study First Submitted: 2016-10-24
• Study First Submitted QC: 2016-10-30
• Study First Posted: 2016-11-01
• Primary Completion: 2017-02
• Study Completion: 2017-02
• Status Verified: 2017-10
• Last Update Submitted: 2017-10-10
• Last Update Posted: 2017-10-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

• revision total hip replacement

Exclusion Criteria

• hematologic disease
• anticoagulant medication
• American Society of Anesthesiologists physical status 4 and 5

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change of FIBTEM	5 minutes before initiation of anesthesia and 5 minutes after finishing operation	FIBTEM: one of the measurements of the rotational thromboelastometry

Secondary Outcome Measures

Name	Time	Method
volume of infused fluid during operation	Period from starting to finishing the operation (During operation, an expected average of 3 hours)	Infused total crystalloid and colloid volume during the operation will be recorded
intraoperative urine output	Period from starting to finishing the operation (During operation, an expected average of 3 hours)
transfusion units	Period from starting to finishing the operation (During operation, an expected average of 3 hours) and postoperative first day	Red blood cell
Hematocrit	postoperative day 4
Platelet count	postoperative day 4
prothrombin time_international normalized ratio	postoperative day 1
activated partial prothrombin time	postoperative day 1
fibrinogen concentration	postoperative day 1
Hemoglobin	postoperative day 4
postoperative bleeding volume	postoperative 72 hours

Trial Locations

Locations (1)

Seoul National University Bundang Hospital; 🇰🇷 Seongnam-si, Gyeonggi-do, Korea, Republic of