Relations Between Hematologic Variables and Postoperative Bleeding and Transfusion in Revision Total Hip Replacement Arthroplasty

Seoul National University Bundang Hospital1 site in 1 country62 target enrollmentApril 2015

ConditionsAvascular Necrosis of Hip Degenerative Hip Joint Disease

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Avascular Necrosis of Hip
Sponsor: Seoul National University Bundang Hospital
Enrollment: 62
Locations: 1
Primary Endpoint: Change of FIBTEM
Status: Completed
Last Updated: 8 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Revision total hip replacement arthroplasty is a surgery having intra- and postoperative substantial blood loss. The investigators will investigate the relationship between the various hematologic variables and postoperative bleeding volume.

Registry

clinicaltrials.gov

Start Date

April 2015

End Date

February 2017

Last Updated

8 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Seoul National University Bundang Hospital

Responsible Party

Principal Investigator

Hyo-Seok Na

Associate Professor

Seoul National University Bundang Hospital

Eligibility Criteria

Inclusion Criteria

•revision total hip replacement

Exclusion Criteria

•hematologic disease
•anticoagulant medication
•American Society of Anesthesiologists physical status 4 and 5

Outcomes

Primary Outcomes

Change of FIBTEM

Time Frame: 5 minutes before initiation of anesthesia and 5 minutes after finishing operation

FIBTEM: one of the measurements of the rotational thromboelastometry

Secondary Outcomes

volume of infused fluid during operation(Period from starting to finishing the operation (During operation, an expected average of 3 hours))
intraoperative urine output(Period from starting to finishing the operation (During operation, an expected average of 3 hours))
transfusion units(Period from starting to finishing the operation (During operation, an expected average of 3 hours) and postoperative first day)
activated partial prothrombin time(postoperative day 1)
postoperative bleeding volume(postoperative 72 hours)
fibrinogen concentration(postoperative day 1)
Hemoglobin(postoperative day 4)
Hematocrit(postoperative day 4)
Platelet count(postoperative day 4)
prothrombin time_international normalized ratio(postoperative day 1)