Effect of Statins on IgG, IgA and IgM Level in Chronic Hemodialysis Patients

Not Applicable

Completed

• Conditions: Chronic Kidney Disease
• Interventions: Drug: Lipitor

• Registration Number: NCT01305317
• Lead Sponsor: Hormozgan University of Medical Sciences

Brief Summary

This is double blind randomized controlled trial on the statins effects on serum IgG, IgA and IgM level in chronic hemodialysis patients in Bandarabbas

Detailed Description

This study is a randomized controlled trial of statins effect on serum IgG, IgA and IgM level on chronic hemodialysis patients in Bandarabbas. The study is carried out in Hormozgan, Iran. Seventy four patient were randomized either to receive atorvastatin in addition of usual treatment or not. The primary outcomes were serum IgG,IgA and IgM level. The secondary outcome was drug side effects.

Study Timeline

• Status Verified: 2006-01
• Study Start: 2007-01
• Primary Completion: 2008-01
• Study Completion: 2010-01
• Study First Submitted: 2011-02-25
• Study First Submitted QC: 2011-02-25
• Study First Posted: 2011-02-28
• Last Update Submitted: 2011-02-28
• Last Update Posted: 2011-03-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 74

Inclusion Criteria

• All chronic hemodialysis patients attending Shahid Mohammadi hospital during the study period
• Accepting to participate in the study

Exclusion Criteria

• Refusing to participate in the study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
lipitor	Lipitor	atorvastatin 20mg daily

Primary Outcome Measures

Name	Time	Method
Serum IgG, IgA and IgM level	6 months

Secondary Outcome Measures

Name	Time	Method
Drug side effects	6 months

Trial Locations

Locations (1)

Shahid Mohammadi hospital; 🇮🇷 Bandar Abbas, Hormozgan, Iran, Islamic Republic of