Study of the Reduction of the Prescriptions of Benzodiazepines and Related

Recruiting

• Conditions: Depression in Old Age

• Registration Number: NCT06107283
• Lead Sponsor: University Hospital, Strasbourg, France

Brief Summary

The significant consumption of Benzodiazepines and related drugs in the elderly outside of good practice recommendations is a major issue in the care of the elderly. Adverse effects have been the subject of numerous studies, leading to falls, addictions and even deaths. The general practitioner is often faced with long-term medication intake which is not consistent with a good benefit/risk balance, but stopping or reducing the dosage remains a problem in current practice.

The Aftercare and Geriatric Rehabilitation services due to their operation (several weeks of hospitalization) seek to adapt the patient's therapies in order to obtain the most convincing benefit/risk balance possible. A reduction or withdrawal of treatments with Benzodiazepines or related drugs are therefore frequently initiated.

Detailed Description

The aim of this research is to quantify among the patients who benefited from a dosage reduction of Benzodiazepines and related drugs during a stay in the Geriatric Care and Aftercare and Rehabilitation department, the number of patients who had an increase of this treatment within 12 weeks following discharge from hospitalization.

Study Timeline

• Study Start: 2023-03-01
• Status Verified: 2023-10
• Study First Submitted: 2023-10-24
• Study First Submitted QC: 2023-10-24
• Last Update Submitted: 2023-10-24
• Study First Posted: 2023-10-30
• Last Update Posted: 2023-10-30
• Primary Completion: 2024-08
• Study Completion: 2024-08-17

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• Major subject (≥ 75 years old)
• Subject discharged from a geriatric Follow-up Care and Rehabilitation service for whom a reduction in the dosage of Benzodiazepines and related drugs was carried out during hospitalization and who returned home (individual or EHPAD) after hospitalization.
• Subject not opposing, after information, the reuse of their data for the purposes of this research.

Exclusion Criteria

• Subject having expressed opposition to participating in the study.
• Subject having treatment with Benzodiazepine to prevent recurrence of epileptic seizures.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The number of patients who had an increase in Benzodiazepines in the 12 weeks following discharge from hospitalization.	12 weeks following discharge from hospitalization.

Trial Locations

Locations (1)

Gériatrie - Service de Soins de Soins Médicaux et de Réadaptation - CHU de Strasbourg - France; 🇫🇷 Strasbourg, France