Aspects of regeneration following digital nerve injury of the hand

Recruiting

Conditions: S64
Injury of nerves at wrist and hand level

Registration Number: DRKS00022894

Lead Sponsor: niversitätsklinikum Regensburg

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 45

Inclusion Criteria

Complete unilateral DN injury
- Single DN injury or multiple DN injuries
- Height of lesion: A1 pulley up to 10 mm proximal to the eponychium (proximal nail fold)
- Primary nerve reconstruction
- Direct reconstruction or reconstruction with grafts (nerve, vein grafts) / nerve conduits

Exclusion Criteria

- Incomplete DN lesions
- Secondary nerve reconstruction (e.g., neuromas)
- Pregnancy / nursing period
- Diabetes mellitus, peripheral polyneuropathy or other neurological diseases interfering with nerve regeneration
- Known nerve compression syndrome of the upper extremity
- Previous surgery / injury to the affected digit
- Patients under legal care

Study & Design

Study Type: observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
- Re-Innervation-Mapping: Assessment of sensory nerve regeneration by detection of the non-sensitive area of the affected digit over a 6 month postoperative period.

Secondary Outcome Measures

Name	Time	Method
- Hoffman-Tinel sign: Evaluation of the nerve regeneration distance.<br>- Static 2-point discrimination (s2PD): Assessment according to the modified Highet classification. <br>- Sharp-blunt discrimination: Differentiation between sharp / blunt sensation in the autonomy area of the injured DN. <br>- Ten-test: Indication of the sensation in the autonomy area of the injured DN in tenths compared to the standard findings.