Chitosan Phonophresis on Cervical IN Smartphone Addicted Users

Not Applicable

Recruiting

• Conditions: Cervical Pain
• Interventions: Drug: Chitosan Phonophresis; Other: selected physical therapy exercise

• Registration Number: NCT06491992
• Lead Sponsor: October 6 University

Brief Summary

A phonophoresis-based drug delivery system is a synchronous approach to improve local drug penetration in neuromuscular diseases associated with neuronal damage, excruciating pain, and local inflammation. Chitosan, a semi-synthetic material, is obtained by partial deacetylation of chitin amines, resulting in copolymers of N-acetylglucosamine and N-glucosamine. Its use has been explored in various biomaterial and medical applications. Chitosan has emerged as a cost-effective, biocompatible, and biodegradable material with many desirable biological properties, improvement of homeostasis and antiviral potential. Chitosan was found to suppress pro-inflammatory cytokines and decreased peripheral nerve edema, the polycationic nature of chitosan allows it to absorb protons, which reduces inflammation and provides an analgesic effect.

Detailed Description

The patients will randomly be divided into two equal groups; the control group which will receive the selected exercise program and the study group will receive the same exercise training program in addition to Chitosan Phonophresis, three times per week for four weeks.

Study Timeline

• Status Verified: 2024-07
• Study Start: 2024-07-01
• Study First Submitted: 2024-07-01
• Study First Submitted QC: 2024-07-01
• Last Update Submitted: 2024-07-01
• Study First Posted: 2024-07-09
• Last Update Posted: 2024-07-09
• Primary Completion: 2024-09-30
• Study Completion: 2024-10-15

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Their age will be ranged from 16-18 years
• body mass index will be 26.58 kg/m2.
• used a smart phone for more than 1 year for at least 2 hours per day
• complaining of neck pain after using a smart phone, addiction to smart phone in accordance with the smart phone addiction scale (SAS)

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Exclusion Criteria

• any previous head and neck injuries or surgeries
• any congenital abnormalities or symptomatic deformity in either the cervical or the lumbar spine
• any uncorrected visual or auditory problems, dizziness, vertigo and headache
• any systematic diseases, any addiction to alcohol, any additive drugs and sedatives within 48 hours previous to tests
• body mass index of subjects over25 kg/m2.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
study group	selected physical therapy exercise	Chitosan Phonophresis intervention
study group	Chitosan Phonophresis	Chitosan Phonophresis intervention
control group	selected physical therapy exercise	the selected exercise program

Primary Outcome Measures

Name	Time	Method
Smartphone Addiction Scale-Short Version (SAS-SV)	four weeks	SAS-SV was psychometrically robust in measuring the severity of smartphone addiction
The visual analogue scale	four weeks	was utilized to evaluate pre- and post-treatment neck pain
Neck disability index	four weeks	assess how neck pain and other symptoms manifested during various functional activities. Ndi had been reported as a reliable (Cronbach's alpha: 0.89) and valid instrument to evaluate self-rated disability in patients with neck pain

Secondary Outcome Measures

Name	Time	Method
Cervical ROM	four weeks	Cervical active ROM will be measured for each participant in the study by digital goniometer device.

Trial Locations

Locations (1)

Lama S Mahmoud; 🇪🇬 Al Jīzah, Select State, Egypt