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Effects of different volumes of ropivacaine for superior brachial plexus block on diaphragmatic paralysis and analgesia

Phase 1
Conditions
Diaphragmatic paralysis
Registration Number
ChiCTR2400088722
Lead Sponsor
Beijing Friendship Hospital, Capital Medical University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

? Patients aged 18-74 years; ? ASA ?~?; ? BMI 18 ~ 30 kg/m2; ? Elective shoulder arthroscopic surgery.

Exclusion Criteria

? Refuse to perform nerve block; ? Coagulation dysfunction; ? Skin infection at the puncture site; ? Allergy to local anesthetics; ? Central system diseases, neuropathy of operative limbs, cervical disc herniation or cervical spondylosis; ? History of severe cardiopulmonary function disease, such as chronic obstructive pulmonary disease or respiratory failure, existing phrenic nerve injury or paralysis on the contralateral side, and lobectomy on the contralateral side; ? Long term chronic pain and related medication history; ? The 24 hour follow up records were incomplete.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Whether the diaphragm muscle was paralyzed 30min after nerve block in the three groups;
Secondary Outcome Measures
NameTimeMethod
The degree of diaphragmatic paralysis, the decrease of SpO2, the occurrence of dyspnea and Horner sign, and the successful time of sensory block in the three groups after 30 minutes of nerve block;Static and dynamic VAS scores were compared between the three groups at 0, 6, 12, and 24 hours after surgery;The duration of upper limb muscle strength, mobility and sensory block on the operative side were evaluated at 0, 6, 12 and 24 hours after surgery in the three groups;Intraoperative dosage of propofol, remifentanil, occurrence of cardiovascular events;Time, dose and frequency of additional analgesic drugs needed 24 hours after surgery;Occurrence of nerve block-related complications within 24 hours after surgery;Basic indicators: gender, age, BMI, ASA grade, comorbidities, history of previous surgery, special medication, type of surgery, operation time, extubation time, PACU residence time;
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