The efficacy of Leucine-enriched essential amino acid supplementation in knee osteoarthritis patients
Not Applicable
Recruiting
- Conditions
- Diseases of the musculoskeletal system and connective tissue
- Registration Number
- KCT0007363
- Lead Sponsor
- Mokdong Himchan Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
This study is planned to be conducted with 70 patients aged between 50 and under 80 with osteoarthritis of the knee, who voluntarily agreed.
Exclusion Criteria
- Patients who underwent knee joint surgery within 6 months from the start date of the experiment
- Patients with a history of infectious arthritis, rheumatoid arthritis, tumors, or fractures
- Patients with hypersensitivity
- Patients with a history of anaphylactic reactions
- Patients or a family member with an autoimmune disease in progress or a history of autoimmune disease
- Patients who are judged to be inappropriate for this study by the judgment of the person in charge of the study, such as those with mental illness
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method imb muscle mass evaluation (DEXA, BMD) evaluation, blood test result evaluation (CBC, Albumin, Blood sugar, Insulin, Interleukin IL-6, Creatine kinase, AST, ALT, BUN, Creatinine, eGFR, 25(OH)D, Total protein , ALP)
- Secondary Outcome Measures
Name Time Method Physical performance evaluation (grip strength evaluation, calf walking speed, sitting and standing 5 times, etc.), KSS, SF-36, WOMAC, VAS