临床试验/NCT02035930

NCT02035930已完成4 期

Effect of Dexmedetomidine on Bispectral Index and Propofol Requirements During Different Menstrual Cycle

Fudan University0 个研究点目标入组 110 人开始时间: 2010年11月最近更新: 2014年1月14日

适应症

干预措施

试验速览

阶段: 4 期
状态: 已完成
发起方: Fudan University
入组人数: 110
主要终点: bispectral index at loss of eyelash reflex

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者记录与标识符相似试验

研究概览

简要总结

The study was done to evaluate the effects of the follicular and luteal phases of the menstrual cycle on sedation level at loss of consciousness and bispectral index reach to 50 during propofol anesthesia, in patients with and without preoperative intravenous dexmedetomidine .

研究设计

研究类型: Interventional
分配方式: Na
干预模型: Single Group
主要目的: Prevention
盲法: Double (Participant, Investigator)

入排标准

年龄范围: 24 Years 至 40 Years（Adult）
性别: Female
接受健康志愿者: 否

入选标准

•a regular menstrual cycle
•elective gynecologic surgery

排除标准

•pregnancy
•breastfeeding
•known hypersensitivity to drugs used in the study protocol;
•use of psychotropic drugs and steroids within 72 hours before the surgery
•central nervous system injury
•renal impairment
•alcoholism and opioid addiction.

研究组 & 干预措施

menstrual cycle,dexmedetomidine

Other

干预措施: dexmedetomidine (Drug)

结局指标

主要结局

bispectral index at loss of eyelash reflex

时间窗: up to 2 years

次要结局

propofol requirements from propofol administered to loss of eyelash reflex and bispectral index reduced to 50(up to 2 years)

研究者

发起方

Fudan University

申办方类型

Other

责任方

Principal Investigator

主要研究者

Geng guiqi

professor

Fudan University

相似试验

已完成

不适用

effect of dexmedetomidine with different induction agents on smooth initiation of anesthesia and better cardiovascular stability during intubation.

CTRI/2018/02/012009none

已完成

4 期

ROLE OF DEXMEDETOMIDINE IN EPIDURAL BLOCK FOR PROLONGED PAIN RELIEF

CTRI/2018/02/011923Dr Rajendra Prasad Government Medical College90

已完成

不适用

Effect of Dexmedetomidine on the Characteristics of High Volume/Low Concentration Ropivacaine in a Caudal Block in PediatricsAmbulatory Orchipexy

NCT02163980Yonsei University80

Unknown

4 期

Effects of Different Doses of Dexmedetomidine on Postoperative Cognitive Dysfunction in Elderly Hypertensive PatientsPostoperative Cognitive Dysfunction

NCT02224443First Affiliated Hospital Xi'an Jiaotong University90

尚未招募

4 期

To compare the effect of drug Dexmedetomidine with a placebo on the blood pressure and heart rate in patients undergoing Laparoscopic gall bladder removal surgery

CTRI/2020/06/026037Dr Dikshita Goswami