A comparison of massage and compression for treatment of head and neck lymphoedema after head and neck cancer treatment.

Not Applicable

• Conditions: Head and neck lymphoedema; head and neck cancer; Cancer - Head and neck; Cardiovascular - Diseases of the vasculature and circulation including the lymphatic system; Physical Medicine / Rehabilitation - Occupational therapy; Physical Medicine / Rehabilitation - Physiotherapy

• Registration Number: ACTRN12619000263190
• Lead Sponsor: Princess Alexandra Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-02-20
• Study Completion: 2020-04-07
• Last Update Posted: 16 February 2021

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 5

Inclusion Criteria

•>18 years of age
•A previous diagnosis of oral, nasopharyngeal, oropharyngeal, laryngeal, or hypopharyngeal cancer treated with chemoradiation, postoperative radiation or definitive radiation with curative intent
•Life expectancy >12months
•Able to provide informed written consent
•MD Anderson Cancer Centre (MDACC) HNL rating >1 indicating soft visible oedema; no pitting, reversible

Exclusion Criteria

•Cancer recurrence
•Previous radiotherapy and/or surgery to the neck, oral, pharyngeal, or laryngeal anatomic structures
•Pharyngolaryngectomy or laryngectomy
•Co-morbidity factors that may result in head and neck oedema and/or lymphoedema, or impact their swallowing and voice function; such as stroke, head and neck trauma, or neurological degenerative diseases.
•Unable to attend follow up appointments at the study site
•Facial hair precluding completion of external lymphoedema assessment
•NIRFLI imaging only: Allergic to indocyanine green, sodium iodide or iodine, over-active thyroid, benign tumours of the thyroid, previous known side effects from indocyanine green injections, kidney failure.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in tissue dielectric constant readings (as indicative of a reduction in head and neck lymphoedema)[6 weeks];Feasibility of conducting a randomised controlled trial comparing compression and manual lymphatic drainage in the management of head and neck lymphoedema. [6 weeks]

Secondary Outcome Measures

Name	Time	Method
Change in tape measurements (as indicative of head and neck lymphoedema)[12 weeks]