Intrathecal Morphine Compared to Intravenous Tramadol and Transversus Abdominal Plane Block for Catheter Related Bladder Discomfort Syndrome
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 33
- 试验地点
- 1
- 主要终点
- catheter related bladder discomfort syndrome
研究概览
简要总结
investigators aim to compare the efficacy of intrathecal morphine, intravenous tramadol and transversus abdominis plane block in the treatment of catheter related bladder discomfort syndrome in patients scheduled for robotic assisted laparoscopic prostatectomy
详细描述
patients scheduled for robot assisted laparoscopic prostatectomy will be treated depending on the belonging group. In the morphine group patients will receive intrathecal morphine 0,15 mg; in the transversus abdominis plane block patients will receive ropivacaine 80 mg; in the tramadol group patients will receive intravenous continuous infusion of tramadol 400 mg for the first 24 hours postoperatively. All data will be collected in the post anesthesia room and in the ward until the first post operative day.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •all patients scheduled for robotic assisted laparoscopic prostatectomy
排除标准
- •coagulation disorders and platelet dysfunction for spinal arm
- •obesity for transversus abdominis plane block arm
- •left ventricular ejection fraction < 30%, end-stage renal disease and neurological disorders for all groups
研究组 & 干预措施
morphine
morphine 150 mcg will be administered intrathecally before surgery by using a 25 Gauge with acre spinal needle
干预措施: intrathecal infusion (Drug)
tramadol
tramadol 400 mg will be administered by using an elastomeric pump for 24 hours after surgery
干预措施: Intravenous Infusion (Drug)
ropivacaine
at the end of surgery transversus abdominis plane block will be performed bilaterally and ropivacaine 80 mg will be used
干预措施: Ropivacaine injection (Drug)
结局指标
主要结局
catheter related bladder discomfort syndrome
时间窗: immediately after surgery
grade 0 to III
次要结局
- pain relief(immediately after surgery)