Intrathecal Morphine Compared to Intravenous Tramadol and Transversus Abdominal Plane Block for Catheter Related Bladder Discomfort Syndrome
Overview
- Phase
- N/A
- Intervention
- intrathecal infusion
- Conditions
- Catheter Related Complication
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Enrollment
- 33
- Locations
- 1
- Primary Endpoint
- catheter related bladder discomfort syndrome
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
investigators aim to compare the efficacy of intrathecal morphine, intravenous tramadol and transversus abdominis plane block in the treatment of catheter related bladder discomfort syndrome in patients scheduled for robotic assisted laparoscopic prostatectomy
Detailed Description
patients scheduled for robot assisted laparoscopic prostatectomy will be treated depending on the belonging group. In the morphine group patients will receive intrathecal morphine 0,15 mg; in the transversus abdominis plane block patients will receive ropivacaine 80 mg; in the tramadol group patients will receive intravenous continuous infusion of tramadol 400 mg for the first 24 hours postoperatively. All data will be collected in the post anesthesia room and in the ward until the first post operative day.
Investigators
Eligibility Criteria
Inclusion Criteria
- •all patients scheduled for robotic assisted laparoscopic prostatectomy
Exclusion Criteria
- •coagulation disorders and platelet dysfunction for spinal arm
- •obesity for transversus abdominis plane block arm
- •left ventricular ejection fraction \< 30%, end-stage renal disease and neurological disorders for all groups
Arms & Interventions
morphine
morphine 150 mcg will be administered intrathecally before surgery by using a 25 Gauge with acre spinal needle
Intervention: intrathecal infusion
tramadol
tramadol 400 mg will be administered by using an elastomeric pump for 24 hours after surgery
Intervention: Intravenous Infusion
ropivacaine
at the end of surgery transversus abdominis plane block will be performed bilaterally and ropivacaine 80 mg will be used
Intervention: Ropivacaine injection
Outcomes
Primary Outcomes
catheter related bladder discomfort syndrome
Time Frame: immediately after surgery
grade 0 to III
Secondary Outcomes
- pain relief(immediately after surgery)