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Clinical Trials/NCT04478929
NCT04478929
Unknown
Not Applicable

Early Detection of Cancer in Cases of Barrett's Esophagus Using Robotic Endoscopy Image Analysis Through Deep Image Retrieval

Leigh Taylor1 site in 1 country300 target enrollmentAugust 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Barrett Esophagus
Sponsor
Leigh Taylor
Enrollment
300
Locations
1
Primary Endpoint
gastroscopy image data set
Last Updated
5 years ago

Overview

Brief Summary

Barrett's oesophagus is a condition in which the area between the oesophagus and stomach no longer closes, allowing acidic contents of the stomach to enter the oesophagus and damage the lining. The project aims to assist clinicians by offering informed biopsy process, in which the system presents the operator with clinical outcomes of patients with visually similar GI tracts. The project goal is to assess the use of artificial intelligence-based similarity detection systems to better inform biopsy placement, increasing the reliability of bi-yearly inspections.

Detailed Description

The project intention is to acquire secondary endoscopy captured data from clinicians to create a sufficient dataset to train a learning system to achieve the stated objective. The data required will feature footage (images/videos) from inside the oesophagus. The preferred data would contain associated diagnosis notes and description, however, data without diagnosis can still be used. All data can and will be anonymised, as personal information will not be useful in this work. The data will be labelled by either researchers, or professional clinicians and prepared ready to feed into a chosen learning AI system. Through an iterative learning process, the chosen AI system will learn to discriminate between severity of Barrett's oesophagus and output optimal biopsy target.

Registry
clinicaltrials.gov
Start Date
August 2020
End Date
August 2021
Last Updated
5 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Leigh Taylor
Responsible Party
Sponsor Investigator
Principal Investigator

Leigh Taylor

Senior Research Officer

University of the West of England

Eligibility Criteria

Inclusion Criteria

  • Attending Southmead Hospital for on OGD
  • Has capacity
  • Initially any indication, later patients with known Barrett's oesophagus

Exclusion Criteria

  • Children (\<18)
  • Patients without capacity
  • Urgent and emergency procedures
  • Limited English

Outcomes

Primary Outcomes

gastroscopy image data set

Time Frame: 12 months

Images collected during routine gastroscopy with examination notes

Study Sites (1)

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