Detection of early neoplasia in Barrett’ esophagus: Do not focus on Barrett’s surveillance – diagnosis is at the indexendoscopy in SSBE with biopsies

• Conditions: C15.5; Lower third of oesophagus

• Registration Number: DRKS00004168
• Lead Sponsor: HSKInnere Medizin 2

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2011-04-30
• Study Start: 2012-06-06
• Results First Posted: 2015-06-15
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 143

Inclusion Criteria

all patients who consecutively presented with a diagnosis of early neoplastic changes (high-grade intraepithelial neoplasia, esophageal adenocarcinoma)

Exclusion Criteria

Lacking data of the criteria mentioned above.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
All patients who consecutively presented with a diagnosis of early neoplastic changes (high-grade intraepithelial neoplasia, esophageal adenocarcinoma) were recorded prospectively. The data noted included the following: length of the Barrett’s segment, reason for esophagogastroduodenoscopy (EGD) at an external institution, external diagnosis, type of evidence of neoplasia (biopsy from a suspicious lesion, biopsy from a conspicuous but not suspicious lesion, four-quadrant biopsy), and diagnosis of macroscopic tumor type by performing an EGD at the expert center.

Secondary Outcome Measures

Name	Time	Method
Is there any dependency of diagnosis of early neoplasia to length of BE or macroscopic tumor type?