Diagnosis of early Barrett’s neoplasia and esophageal squamous cell neoplasia by electrical bio-impedance spectroscopy in human tissue

• Conditions: C15.9; K22.7; Oesophagus, unspecified; Barrett oesophagus

• Registration Number: DRKS00003358
• Lead Sponsor: Dr. Horst-Schmidt-Klinik WiesbadenII. Medizinische Klinik

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2011-11-28
• Study Completion: 2012-02-08
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 23

Inclusion Criteria

Known esophageal cancer and planned for endoscopic resection

Exclusion Criteria

1. Missing consent / agreement
2. Patient in bad condition for endoscopy or endoscopic resection
3. Patients with coagulopathy or anticoagulative medication which is a contraindication for endoscopy

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary endpoint of the study is to demonstrate that different types of esophageal tissue can be distinguished by their electrical impedance properties. For this purpose the tissue is measured by an electrode directly after resection. The measurement is done over 17 different frequencies in [ohm]. The result is shown as a graph. Subsequently the histological results are compared to the graphs. Finally significant differences are evaluated.

Secondary Outcome Measures

Name	Time	Method
Differences in electrical impedance properties between different stages of early esophageal cancer. The measurments are done in the same way as mentioned at the point of primary outcome