Efficacy Of Adjunctive N-Acetyl Cysteine On Craving In Patients With Opioid Dependence Syndrome
Not Applicable
- Conditions
- Health Condition 1: F112- Opioid dependence
- Registration Number
- CTRI/2023/04/051775
- Lead Sponsor
- Central Institute Of Psychiatry
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. In-patients of male sex aged between 18-60 years
2. Those who fulfill the criteria for Mental and Behavioral disorders due to use of Opioids, Dependence syndrome (F11. 2X) according to International Classification of Diseases 10th version (ICD-10) - Diagnostic Criteria for Research (DCR) by World Health Organization (WHO, 1992)
3. Subjects giving written informed consent.
Exclusion Criteria
1. Patient with any co morbid substance dependence with opioid (except Nicotine and Caffeine)
2. Patients with currently serious physical problem and organic brain disorder
3. History of any other psychiatric illness or mental retardation
4. Patients having any metallic implants/parts in body.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction in scores of OCDUS and DDQ .Timepoint: Reduction in scores of OCDUS and DDQ at baseline and after 4 weeks of treatment.
- Secondary Outcome Measures
Name Time Method Effect on craving and its relationship with Glutamate level in Nucleus Accumbens.Timepoint: Effect on craving and its relationship with Glutamate level in Nucleus Accumbens at baseline and 4 weeks after treatment.