Protocol of Management of Major Pediatric Burn in Intensive Care Unit

Not Applicable

• Conditions: Burns
• Interventions: Other: protocol of management of major burn in intensive care unit

• Registration Number: NCT04192942
• Lead Sponsor: Assiut University

Brief Summary

Decrease mortality and morbidity in major pediatric burns

Detailed Description

The goals of initial patient management include preservation of overall homeostasis while appreciating the physiologic challenges that the burn injury poses to the body. Major burn injury not only results in local damage from the inciting injury, but in many cases results in multisystem injury. Initial efforts are focused on resuscitation, maintaining hemodynamic stability, and airway management. Intermediate efforts are focused on managing the multi-organ failure that results from systemic inflammatory mediators that result in diffuse capillary leak and surgical therapy. Finally, efforts shift to issues with chronic wound healing, pain management, restoration of functional capabilities, and rehabilitation.. Burn injury in children continues to be a major epidemiologic problem around the globe. Nearly a fourth of all burn injuries occur in children under the age of 16, of whom the majority are under the age of five This provides a team of pediatricians, surgeons, anesthesiologists, intensivists, nurses, respiratory therapists, and other healthcare providers with a unique opportunity to make a multidisciplinary collaborative effort.

Study Timeline

• Study First Submitted: 2019-10-14
• Status Verified: 2019-12
• Study Start: 2019-12
• Study First Submitted QC: 2019-12-09
• Last Update Submitted: 2019-12-09
• Study First Posted: 2019-12-10
• Last Update Posted: 2019-12-10
• Primary Completion: 2021-06
• Study Completion: 2021-09

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• age below 18 year
• children with burn between 20% to 50% of total body surface area
• recent burn within 48 hour

Exclusion Criteria

• old burn over 48 hour after injury -burnt surface area less than 20% of total body surface area - -
• burnt surface area more than 50% of total body surface area
• old age over 18 year

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
intensive care management	protocol of management of major burn in intensive care unit	Administration of childern with major burn in intensive care to improve out comes

Primary Outcome Measures

Name	Time	Method
Changing mortality rate	baseline	Change mortality rate to lowest degree which due too severe burn less than 20% of childern with major burn

Secondary Outcome Measures

Name	Time	Method
Changing hospital stay time	Baseline	Hospital stay less than 30 days