Urine Biomarkers for Renal Function Monitoring in Preterm Infants

Completed

• Conditions: Premature Infant

• Registration Number: NCT02813109
• Lead Sponsor: Inha University Hospital

Brief Summary

The true renal function of preterm infants is difficult to evaluate. Serum creatinine (Cr) levels in infants are unreliable as a detector of renal function in the first few days of life because they may continue to reflect maternal levels. Although few candidates appear to be a useful biomarker for kidney injury, scant reference data on these biomarker in preterm infants exist, and studies have yielded conflicting results. Therefore, we aimed to determine the reliable urinary biomarkers to detect kidney injuries in preterm infants.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-06
• Study First Submitted: 2016-06-20
• Study First Submitted QC: 2016-06-21
• Study First Posted: 2016-06-24
• Primary Completion: 2017-02-15
• Study Completion: 2017-03-02
• Status Verified: 2017-04
• Last Update Submitted: 2017-04-27
• Last Update Posted: 2017-04-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 83

Inclusion Criteria

• premature infants born before 37 weeks of gestational age

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Exclusion Criteria

• cardiac or renal anomalies
• transferred in 2 days after birth from other hospitals

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
correlation of urinary NGAL (neutrophil-gelatinase-associated lipocalin) with serum creatinine	postnatal 7day

Trial Locations

Locations (2)

Inha University Hospital; 🇰🇷 Incheon, Korea, Republic of

Hallym University Medical Center - Kangnam; 🇰🇷 Seoul, Korea, Republic of