Investigation of Respiratory Muscle Strength and Aerobic Capacity in Patients With Scleroderma
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Scleroderma
- Sponsor
- Firat University
- Enrollment
- 15
- Locations
- 1
- Primary Endpoint
- Respiratory muscle strength assessment
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
Primary aim of this study was to compare respiratory muscle strength, aerobic capacity, dyspnea, pulmonary function tests and fatigue values with healthy controls. The secondary aim was to evaluate the relationship between respiratory muscle strength and other parameters in these patients and to examine the factors that may affect respiratory muscle strength. Respiratory muscle strength, aerobic capacity, respiratory function tests and fatigue will be evaluated
Detailed Description
Scleroderma is a systemic connective tissue disease characterized by progressive thickening of the skin, the etiology of which has not been fully elucidated, in which microvascular damage, immune activation and fibrosis play a role. Primary aim of this study was to compare respiratory muscle strength, aerobic capacity, dyspnea, pulmonary function tests and fatigue values with healthy controls. The secondary aim was to evaluate the relationship between respiratory muscle strength and other parameters in these patients and to examine the factors that may affect respiratory muscle strength. The study will include 15 patients and 15 healthy individuals of the same age and gender. Respiratory muscle strength, aerobic capacity, respiratory function tests and fatigue will be evaluated
Investigators
Songül Bağlan Yentür
Firat University
Firat University
Eligibility Criteria
Inclusion Criteria
- •Being diagnosed with Ssk according to ACR/EULAR criteria
- •Stable medical treatment for 3 months
Exclusion Criteria
- •Having a regular exercise habit (doing regular exercise at least once a week for the last 3 months)
- •Comorbidity with another chronic disease that may affect aerobic capacity or respiratory muscle strength
- •Having concomitant acute respiratory diseases
- •Having a smoking habit
- •History of orthopedic or neurologic disease in the lower extremities that may prevent cycling
Outcomes
Primary Outcomes
Respiratory muscle strength assessment
Time Frame: 5 minutes
Respiratory muscle strength will be assessed with an intraoral pressure gauge. These are the intraoral pressures measured at maximal respiration against a valve that closes the airways. When applying MIP, the patient is asked to perform maximal expiration. As a result, the patient is asked to maximally inspire against the closed airway and maintain this for 1-3 seconds. MEP, on the other hand, after maximal inspiration, the patient is asked to perform maximal expiration against the closed airway for 1-3 seconds.
Secondary Outcomes
- Aerobic capacity assessment(10 minutes)
- Fatigue assessment(2 minutes)
- Pulmonary function test(5 minutes)