TCTR20230901006已完成3 期
Efficacy of vaginal progesterone for maintenance therapy in arrested preterm labor: A Randomized Controlled Trial
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 80
研究概览
简要总结
High-dose vaginal progesterone, as a maintenance agent, efficiently prolongs latency delivery day, reduces the rate of preterm birth and improves birth weight. However, it fails to delay the shortening of the cervix and does not decrease the rate of NICU admission.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- N/A (No limit) 至 N/A (No limit)（—）
- 性别
- Female
入选标准
- •Pregnant women presented with preterm labor at gestational age of 24 completed weeks to 33 weeks and 6 days
排除标准
- •lethal fetal anomaly
- •dead fetus in utero
- •non-reassuring fetal status
- •preeclampsia with severe features
- •unstable maternal vital signs
- •chorioamnionitis
- •patient allergic to progesterone or progestrogen
- •multifetal gestations
- •placenta previa
- •cervical os open more than 4 cm
- •history of cervical cerclage in this pregnancy
- •history of vaginal progesterone used in this pregnancy due to others indication for example ; short cervix
研究者
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终止
3 期
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