Different Lipid Soluble Opioids for Gynecologic Laparoscopic Surgery Postoperative Patient-controlled Analgesia --- a Double Blind Randomized Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 180
- 主要终点
- visual analogue pain scores
研究概览
简要总结
The investigators noticed that Body Fat Ratio might have great influence on the efficacy of different lipid soluble anesthetics. The objective of this clinical trial was to compare the effect of that Body Fat Ratio on the efficacy of different lipid soluble anesthetics.
详细描述
The objective of this clinical trial was to compare the effect of that Body Fat Ratio on the efficacy of different lipid soluble anesthetics.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 20 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •American Society of Anesthesiologists grade I-II
- •adults aged over 20 and below 50 years old,
- •non-smoker,
- •with normal hepatic and renal function.
排除标准
- •any kind of mental disorder or
- •history use of analgesics for more than 10 consecutive days,
- •asthma; and
- •those with digestion tract disorder who would get nausea or vomiting much more easily than normal people.
研究组 & 干预措施
low body fat percentage
body fat percentage less than 30%
干预措施: Morphine (Drug)
low body fat percentage
body fat percentage less than 30%
干预措施: Sufentanil (R30730, brand name Sufenta) (Drug)
low body fat percentage
body fat percentage less than 30%
干预措施: Sufentanil (R30730, brand name Sufenta) + Morphine (Drug)
heigh body fat percentage
body fat percentage more than 30%
干预措施: Sufentanil (R30730, brand name Sufenta) (Drug)
heigh body fat percentage
body fat percentage more than 30%
干预措施: Sufentanil (R30730, brand name Sufenta) + Morphine (Drug)
heigh body fat percentage
body fat percentage more than 30%
干预措施: Morphine (Drug)
结局指标
主要结局
visual analogue pain scores
时间窗: 24hour
we evaluate visual analogue pain scores at different time points within 24 hours after surgery
次要结局
- nausea & vomiting(24hour)
研究者
ZhouYan
M.D
Peking University First Hospital