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临床试验/NCT06123208
NCT06123208已完成不适用

The Influence of the Resistant Starch and Protein Content of Pulses on Substrate Oxidation

USDA Grand Forks Human Nutrition Research Center2 个研究点 分布在 1 个国家目标入组 36 人开始时间: 2023年10月30日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
36
试验地点
2
主要终点
Acute effects of consuming processed pulse-based food products on substrate utilization

研究概览

简要总结

The purpose of this research is to test how eating a meal containing beans impacts how participants' bodies use food for energy.

详细描述

The objective of this project is to test whether consuming a whole food that naturally contains resistant starch (RS), such as pulses, increases fat oxidation. The primary hypothesis is that consuming a RS-rich meal in which the RS is derived from a whole food (i.e., pinto beans, pinto bean flour) will increase postprandial fat oxidation to a greater extent than consuming a meal low in RS but containing the same amount of energy and macronutrient content.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Other
盲法
None

入排标准

年龄范围
19 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • BMI >18.5 or <30 kg/m2
  • Ability to understand and sign the consent form
  • Ability of transportation (i.e., participants must be able to provide their own transportation to the Grand Forks Human Nutrition Research Center)
  • Non-smoking or use of other tobacco products, including e-cigarettes
  • Not taking steroid-based medications; not planning to or currently attempting to gain or lose weight
  • All females of childbearing age must be on birth control for a minimum of 3 months prior to start of study

排除标准

  • Inability or unwillingness to consume any food item in the test meals
  • More than a 10% change in body weight within the past 2 months
  • Participation in a weight loss diet/exercise program
  • Current or planned pregnancy
  • Lactation
  • Uncontrolled hypertension (systolic >160 mmHg or diastolic >100 mmHg)
  • Diagnosed cardiovascular, pulmonary, skeletal and metabolic diseases
  • Fasting glucose > 100 mg/dL or non-fasting (1-2 hours after eating) >140 mg/dL
  • Using medications known to affect appetite, blood lipids, body composition, body weight, or food intake (appetite control drugs, steroids, antidepressants)
  • Non-English speaking

结局指标

主要结局

Acute effects of consuming processed pulse-based food products on substrate utilization

时间窗: 5 hours after meal consumption

The effect of consuming whole beans or bean-derived flour on the use of fat, carbohydrate, and protein for energy will be determine using whole room calorimetry. Fat, carbohydrate, and protein oxidation will be calculated as an absolute amount of grams per day and as a percentage of energy expenditure.

次要结局

未报告次要终点

研究者

发起方
USDA Grand Forks Human Nutrition Research Center
申办方类型
Fed
责任方
Sponsor

研究点 (2)

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