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Clinical Trials/NCT01778140
NCT01778140
Unknown
N/A

Randomized Controlled Trial: Comparing Effects of Patient-Specific Versus Non-Patient-Specific Computerized Reminder System to Reduce Contrast-Induced Nephropathy

Taipei Medical University1 site in 1 country90 target enrollmentJanuary 2012

Overview

Phase
N/A
Intervention
Not specified
Conditions
Radiographic Contrast Agent Nephropathy
Sponsor
Taipei Medical University
Enrollment
90
Locations
1
Primary Endpoint
The percentage of contrast-enhanced imaging(CEI) orders with high CIN risk
Last Updated
13 years ago

Overview

Brief Summary

The investigators hypothesize that a Clinical Decision Support System (CDSS) designed with "Patient-Specific" reminders yields superior performance than that with "Non-patient-specific" reminders in preventing contrast-induced nephropathy.

Detailed Description

We hypothesize that a clinical decision support system (CDSS) designed with "Patient-specific" reminders yields superior performance than that with "Non-patient-specific" reminders in preventing contrast-induced nephropathy. A 3-arm randomized controlled trial (RCT) will be performed by cluster randomization using physicians as the unit of allocation. Physicians in 3 university medical centers will be randomly assigned into 1) patient-specific arm with Anti Contrast-Induced-Nephropathy(Anti-CIN) reminder, 2) non-patient-specific reminder arm, and 3) the control arm without any reminders, respectively. The patient-specific alert, Anti-CIN system, is designed as a real-time CDSS implementation on CPOE for monitoring physician's contrast-enhanced CT and IVP orders. Computerized pop-up reminders provide the patient-specific encounters with optimal decision options when patients are at a high CIN risk or patients with unknown risk factors are encountered. Non-patient-specific reminders always pop up no matter whether the patient is at a high risk or not.

Registry
clinicaltrials.gov
Start Date
January 2012
End Date
August 2013
Last Updated
13 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Our intervention targets are physicians but not patients. All physicians working in the hospital may join this trial.

Exclusion Criteria

  • The physician who never orders a CT scan or IVU study will be excluded
  • The physician who never operates the CPOE by himself or herself will be excluded

Outcomes

Primary Outcomes

The percentage of contrast-enhanced imaging(CEI) orders with high CIN risk

Time Frame: Physicains who participated in this trial will be followed for an expected average of 12 months

The number of CEI ordered for patients at high CIN risk, divided by the total number of CEI orders. \[CEI\]: contrast-enhanced image studies,such as CT or IVU. \[CIN\]: contrast-induced nephropathy

Secondary Outcomes

  • The order elimination rate of high CIN risk orders attributed to the computerized reminder(Physicains who participated in this trial will be followed for an expected average of 12 months)

Study Sites (1)

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