NCT03695991Unknown不适用
Effect of Per-cutaneous Nephrosotomy Drainage on Radioisotope Imaging of Hydronephrotic Kidneys
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 62
- 主要终点
- The rate of increase in glomerular filtration rate after intervention
研究概览
简要总结
Hydronephrosis describes a condition of urine-filled dilation of the collecting system. Normally, urine flows through the urinary tract with minimal or low pressure. If the build-up of excess fluid in the urinary collecting system continues, there will be an increase in pressure and atrophy of renal cortex. If hydronephrosis is left untreated for a long time, renal damage with permanent loss of function occurs
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients for whom a percutaneous nephrostomy is indicated provided that the hydronephrosis is advanced ( parenchymal thickness not more than 5 mm ) 2) Patients for whom a nephrectomy is planned for a seemingly poorly functioning kidney along with either
排除标准
- •Target kidney is the only functioning or better functioning kidney or otherwise substantially contributing to the total renal function, so nephrectomy is not likely.
- •Emergency cases where the general condition of the patient cannot withstand the logistics of undergoing a radioisotope study eg
- •Malignancy in the target kidney
- •Patients unlikely to undergo a nephrectomy
结局指标
主要结局
The rate of increase in glomerular filtration rate after intervention
时间窗: 3 weeks
the radioisotope measurement of glomerular filtration rate will be done before and after insertion of percutaneous nephrostomy tube
次要结局
未报告次要终点
研究者
Abdelrahman Atef Ali
Principal investigator
Assiut University
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