Metacognition in Semantic Dementia: Comparison With Alzheimer's Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 7
- 主要终点
- Metacognitive bias on the semantic retrospective judgment task
研究概览
简要总结
This study aims at exploring patients' ability to monitor their own memory performance depending on their primary deficit and the type of memory involved in the criterion task. The goal is to evaluate if semantic dementia (SD) and Alzheimer's disease (AD) differently affect patients' awareness of their memory abilities.
详细描述
Patients who will give their informed non-opposition will be included. Participants will undergo 6 metacognitive tasks in which they will be tested on newly learnt information (i.e., episodic memory) or prior knowledge (i.e., semantic memory) and asked to evaluate their performance either prior or after the test. Correlation between their evaluation and their actual performance will be measured. Performance and correlations will be compared across groups.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •native French-speakers
- •normal or corrected-to-normal vision
- •for patients ONLY : doctor-approved diagnosis of semantic dementia or Alzheimer's disease
- •for healthy participants ONLY: score above 27 on the MMSE
- •non-opposition in participation
排除标准
- •other neurological/ psychiatric disorder, or cognitive disorder that might affect general cognition
- •drug or alcohol abuse
结局指标
主要结局
Metacognitive bias on the semantic retrospective judgment task
时间窗: End of study : around May 2022
Metacognitive bias will be assessed by subtracting the mean proportion of the metacognitive judgments to the actual memory performance. Bias will range from -1 (underestimation) to 1 (overestimation).
Metacognitive accuracy on the semantic retrospective judgment task
时间窗: End of study : around May 2022
Metacognitive accuracy will be assessed by calculating a gamma correlation for each participant. Metacognition accuracy allows to evaluate people's ability to discriminate correct responses from incorrect responses. Gamma correlation range from -1 to 1.
Metacognitive bias on episodic global judgment task
时间窗: End of study : around May 2022
Metacognitive bias will be assessed by subtracting the mean proportion of the metacognitive judgments to the actual memory performance. Bias will range from -1 (underestimation) to 1 (overestimation).
Metacognitive accuracy on the semantic predictive judgment task
时间窗: End of study : around May 2022
Metacognitive accuracy will be assessed by calculating a gamma correlation for each participant. Metacognition accuracy allows to evaluate people's ability to discriminate correct responses from incorrect responses. Gamma correlation range from -1 to 1.
Metacognitive bias on semantic global judgment task
时间窗: End of study : around May 2022
Metacognitive bias will be assessed by subtracting the mean proportion of the metacognitive judgments to the actual memory performance. Bias will range from -1 (underestimation) to 1 (overestimation).
Metacognitive bias on the episodic predictive judgment task
时间窗: End of study : around May 2022
Metacognitive bias will be assessed by subtracting the mean proportion of the metacognitive judgments to the actual memory performance. Bias will range from -1 (underestimation) to 1 (overestimation).
Metacognitive bias on the semantic predictive judgment task
时间窗: End of study : around May 2022
Metacognitive bias will be assessed by subtracting the mean proportion of the metacognitive judgments to the actual memory performance. Bias will range from -1 (underestimation) to 1 (overestimation).
Metacognitive bias on the episodic retrospective judgment task
时间窗: End of study : around May 2022
Metacognitive bias will be assessed by subtracting the mean proportion of the metacognitive judgments to the actual memory performance. Bias will range from -1 (underestimation) to 1 (overestimation).
Metacognitive accuracy on the episodic predictive judgment task
时间窗: End of study : around May 2022
Metacognitive accuracy will be assessed by calculating a gamma correlation for each participant. Metacognition accuracy allows to evaluate people's ability to discriminate correct responses from incorrect responses. Gamma correlation range from -1 to 1.
Metacognitive accuracy on the episodic retrospective judgment task
时间窗: End of study : around May 2022
Metacognitive accuracy will be assessed by calculating a gamma correlation for each participant. Metacognition accuracy allows to evaluate people's ability to discriminate correct responses from incorrect responses. Gamma correlation range from -1 to 1.
次要结局
未报告次要终点