Study of thyroid profile in patients with chronic kidney disease in tertiary care center
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 105
- 试验地点
- 1
- 主要终点
- The primary outcome of the study could be defined as the prevalence of thyroid function abnormalities (such as subclinical hypothyroidism, overt hypothyroidism, hyperthyroidism, and low T3 syndrome) in patients with chronic kidney disease (CKD), categorized according to different stages.
研究概览
简要总结
The study proposes to investigate the thyroid profile in patients with chronic kidney disease (CKD) in a tertiary care center. The rationale underscores the importance of understanding the relationship between thyroid hormones and CKD due to overlapping symptoms and potential treatment implications. The objectives include evaluating thyroid function, correlating abnormalities with CKD stages, assessing quality of life, and monitoring changes after treatment. Ethical approval and informed consent will be obtained, with data collected through patient history, examination, and laboratory tests. Statistical analysis will be conducted using SPSS software. The study aims to contribute valuable insights into thyroid function in CKD patients, potentially informing clinical management strategies.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •All patients of Chronic Kidney Disease above the age of 18 years.
- •Patients voluntarily willing to give informed consent will be taken for this study.
排除标准
- •Family history of thyroid disorder.
- •Known case of thyroid disorders whether having medication or not.
- •History of any surgery or any radiological intervention to thyroid gland.
- •Patients on drugs altering thyroid profile such as amiodarone, phenytoin, oestrogen pills and iodine containing drugs.
- •Pregnant females.
结局指标
主要结局
The primary outcome of the study could be defined as the prevalence of thyroid function abnormalities (such as subclinical hypothyroidism, overt hypothyroidism, hyperthyroidism, and low T3 syndrome) in patients with chronic kidney disease (CKD), categorized according to different stages.
时间窗: BASELINE AND 12 WEEKS
次要结局
- This study aims to examine thyroid function in chronic kidney disease (CKD) patients across different stages and assess the prevalence of thyroid abnormalities. Secondary outcomes include investigating correlations between thyroid function and CKD stages, as well as changes in quality of life, estimated glomerular filtration rate (eGFR), and Body Mass Index (BMI) after 3 months of treatment in non-dialysis CKD patients.(1 Month)
研究者
Dr Sushrut Gupta
Datta Meghe Institute of Higher Education and Research