The Effect of Ultrasound-guided Erector Spinae Plane Block on Postoperative Analgesia in Radiofrequency Ablation Therapy
Overview
- Phase
- Not Applicable
- Intervention
- ESPB group
- Conditions
- Hepatocellular Carcinoma
- Sponsor
- National Taiwan University Hospital
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Visual analogue pain scale at postoperative day one
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
This is a double blind, randomized controlled trial to evaluate the efficacy of ESPB(Erector Spinae Plane Block) on postoperative analgesia in RFA( Radiofrequency Ablation therapy). We will include 80 patients, and randomly assign to ESPB(Chirocaine) group and control group(normal saline).We deduce Erector spinae plane block can be use as a postoperative analgesic way for patients who receive radiofrequency ablation of hepatocellular carcinoma.
Detailed Description
Computed tomography guided radiofrequency ablation of hepatocellular carcinoma(HCC) has became a popular way to treat HCC. Although the wound is small and the patients can discharge on the next day, they have to suffer from moderate to severe pain. Nowadays Erector spinae plane block has been applied to many surgery as a postoperative analgesic strategy. We deduce Erector spinae plane block can be use as a postoperative analgesic way for patients who receive radiofrequency ablation of hepatocellular carcinoma. Besides, we will add contrast medium to evaluate the spread area of local anesthetics.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Arms & Interventions
ESPB group
ESPB injection at T10 region with levobupivacaine 100mg (20 ml)+ Omnipaque10 ml
Intervention: ESPB group
Control group
ESPB injection at T10 region with 0.9% normal saline 20ml + Omnipaque10ml
Intervention: Control group
Outcomes
Primary Outcomes
Visual analogue pain scale at postoperative day one
Time Frame: approximately 12-24 hrs
We will assess the pain intensity by using a 100-mm visual analogue scale at postoperative day one
Drug spread level of erector spinae plane block
Time Frame: approximately 2-3 hrs
We will assess the numbers of vertebral levels of erector spinae block drug spreading by using computed tomography
Secondary Outcomes
- Postoperative recovery quality(approximately 2 days)
- Visual analogue pain scale at post-anesthesia care unit(approximately 3 hours)