Erector Spinae Plane Block (ESPB): A New Technique for Perioperative Pain Control in Patients Undergoing Surgery Through a Flank or Anterior Subcostal Incision.
Overview
- Phase
- Phase 4
- Intervention
- Ropivacaine
- Conditions
- Nephrectomy
- Sponsor
- Milton S. Hershey Medical Center
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Pain Scores Using the Visual Analogue Pain Scale From Zero Pain to Level Ten Pain
- Status
- Terminated
- Last Updated
- last year
Overview
Brief Summary
Using a randomized double-blinded study design, the study goal is to evaluate the superiority of Erector Spinae Plane block (ESPB) in the peri-operative pain management of patients undergoing surgery through a flank or anterior subcostal incision as compared to the standard of care of using IV and oral opiates.
Detailed Description
40 subjects will be randomized in to 2 groups, with 20 in each group. * Group 1. Erector spinae plane block (ESPB) (containing Ropivacaine) * Group 2. Sham Erector spinae plane block. (SESPB) (with normal saline)
Investigators
Alireza Aminsharifi
Assistant Professor of Surgery
Milton S. Hershey Medical Center
Eligibility Criteria
Inclusion Criteria
- •Consenting adults age 18-85
- •American Society of Anesthesiologists (ASA) Physical Status classification I to III
- •Planned to be hospitalized for at least 24 hours post-op
- •Cognitive capacity to use the visual analogic scale (VAS) and complete the patient satisfaction survey
Exclusion Criteria
- •Patient refusal
- •Patients with allergies to local anesthetics or opiates (hydromorphone or oxycodone)
- •Scoliosis
- •Patients with chronic pain syndromes or who are on chronic pain medications/other neurologic medication of more than 3 months or whom have neuromodulators/stimulators
- •Concurrent surgeries requiring additional incisions on the body
Arms & Interventions
Ropivicaine
Erector Spinae Block of 20ml 0.5% ropivicaine bolus, connected to a pump containing 0.2% ropivicaine receiving 15ml every 3 hrs.
Intervention: Ropivacaine
Normal Saline
Erector Spinae Block of 20ml normal saline placebo bolus, then connected to pump of normal saline receiving 15ml every 3 hrs.
Intervention: Normal saline
Outcomes
Primary Outcomes
Pain Scores Using the Visual Analogue Pain Scale From Zero Pain to Level Ten Pain
Time Frame: Aggregate pain scores for average length of hospital stay which is 3 days
Data will be collected via the electronic medical record and begin following patient randomization. The Visual Analogue Scale pain scales will be administered and collected on Post Operative Days 1, 2 and 3. Minimum value = 0 No Pain, Maximum value = 10 Worst possible, unbearable, excruciating pain