Comparison of Erector Spina Plane Block and Thoracic Epidural Block in Breast Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Breast Neoplasms
- Sponsor
- Inonu University
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Sympathetic block level evaluation by hemodynamic data
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
The aim of this randomised controlled and double-blind study, is to compare the effects of erector spinae plane (ESP) and thoracic epidural (TEA) blocks on peri-operative hemodynamics and analgesia in patients undergoing unilateral mastectomies due to malignancy.
Detailed Description
Patients will be randomised into two groups as Group E (those who received general anesthesia after the erector spina plan block) and Group T (those who received general anesthesia after thoracic epidural block). After the block skin conductivity (galvanic skin response - GSR), body temperature changes, sympathetic and sensory block levels, peri-operative hemodynamic data, postoperative pain scores and analgesic consumption will be recorded.
Investigators
Gulay ERDOGAN KAYHAN
Professor, MD
Inonu University
Eligibility Criteria
Inclusion Criteria
- •ASA(American Society of Anesthesiologist) physical classification I-III
- •Patients undergoing unilateral mastectomies due to malignancy
Exclusion Criteria
- •Active infection at the intervention site
- •History of coagulopathy or anticoagulant use (less time has passed before peripheral and central blocks)
- •Major cardiac, pulmonary, renal and neurological diseases
- •Autonomic neuropathy or use of drugs that affect autonomic function
- •Patients with type 1 diabetes or insulin dependent type 2 diabetes over 10 years
- •Allergic to local anesthetics;
- •Patients who are uncooperative or have psychiatric problems
- •Morbidly obese (body mass index \> 35 kg/m2)
Outcomes
Primary Outcomes
Sympathetic block level evaluation by hemodynamic data
Time Frame: 45 minutes after block administration
Peri-operative heart rate and mean arterial pressure will be recorded
Sensorial block level evaluation
Time Frame: 45 minutes after block administration
By pin-prick test
Sympathetic block level evaluation with skin temperature
Time Frame: 45 minutes after block administration
Skin temperature of bilateral thorax will be measured
Sympathetic block level evaluation with skin conductivity
Time Frame: 45 minutes after block administration
Skin conductivity will be measured by galvanic skin response (GSR)
Sympathetic block level evaluation with hot cold test
Time Frame: 45 minutes after block administration
Hot cold test of bilateral thorax will be measured
Secondary Outcomes
- Postoperative pain scores(24 hours after operation)
- intraoperative hemodynamic data(During the operation)
- Rescue analgesics consumption(24 hours after operation)