Effect of Different Plane Blocks on Quality of Recovery and Postoperative Pain After Laparoscopic Hysterectomy

Not Applicable

Recruiting

• Conditions: Post Operative Pain

• Registration Number: NCT05780333
• Lead Sponsor: Mentese State Hospital

Brief Summary

The goal of this clinical trial is to evaluate in effect of tap block and esp block on quality of recovery and postoperative pain after laparoscopic hysterectomy. The main question it aims to answer are: Are these two plane blocks used superior to each other? Participants;

* will fill out the preoperative questionnaire

* will fill out the postoperative questionnaire

* will report their pain status according to the NRS score

Detailed Description

Standard management of acute pain after surgery consists mainly of systemic opioid narcotics and nonsteroidal anti-inflammatory drugs (NSAIDs). Generally, opiates and NSAIDs are not completely effective at managing pain, and they carry significant risk of addiction and overdose, particularly with prolonged or increased dosing. The concept of multimodal or ''balanced'' analgesia is rapidly becoming the 'standard of care' for preventing post-operative pain. It consists of the use of combinations of analgesics of different classes with different sites of action in an attempt to provide superior pain relief with reduced analgesic related side effects. Local anesthetic injection to block specific nerves has been widely recognized as a useful adjunct in a multimodal approach to postoperative pain management.

Erector Spinae Plane (ESP) block is a recently described plane block designed to block the dorsal and ventral rami of the spinal nerves. And this block provides visceral and somatic pain block.

Transversus Abdominis plane (TAP) block involves the injection of LA between the transversus abdominis (TA) and internal oblique (IO) muscles.This interfascial plane contains the intercostal, subcostal, iliohypogastric, and ilioinguinal nerves. These nerves give sensation to the anterior and lateral abdominal wall as well as the parietal peritoneum, providing only somatic and not visceral analgesia.

Study Timeline

• Study Start: 2023-01-27
• Status Verified: 2023-03
• Study First Submitted: 2023-03-04
• Study First Submitted QC: 2023-03-20
• Study First Posted: 2023-03-22
• Last Update Submitted: 2023-03-23
• Last Update Posted: 2023-03-27
• Primary Completion: 2023-06-30
• Study Completion: 2023-07-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

• Female patients who will undergo hysterectomy under elective conditions
• 18- 65 years
• ASA I-II patients

Exclusion Criteria

• Refusal during registration, request to be excluded from the study, failure to give informed consent
• Under 18 years old and upper 65 years old
• ASA III-IV patients
• Chronic opioid use
• Presence of infection at the injection site
• Renal failure / Liver failure
• Bupivacaine sensitivity
• Use of anticoagulants
• BMI < 18,5 , BMI >35

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Quality of Recovery 40 Questionnaire	24 hours after surgery.	The global Quality of Recovery-40 aggregate score is a scale from (1 to 5, where: 1 = very poor and 5 = excellent)

Secondary Outcome Measures

Name	Time	Method
Postoperative pain	24 hours after surgery.	is a numerical rating scale from (1 to 10, where: 1 is the mildest and 10 the worst possible)

Trial Locations

Locations (1)

Pelin Dilsiz Eker; 🇹🇷 Muğla, Menteşe, Turkey