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Xarelto [SPAF-QOL] Post-marketing Surveillance in Japan

Completed
Conditions
Non-valvular Atrial Fibrillation (NVAF)
Interventions
Registration Number
NCT01598051
Lead Sponsor
Bayer
Brief Summary

The objective of this study is to understand if Rivaroxaban can improve treatment satisfaction of Warfarin patients and assess the safety and effectiveness of Xarelto in real clinical practice.

A total of 725 patients are to be enrolled and followed for a 6 months.period. QOL survey will be conducted at month 0, 3, 6 using ACTS/TSQM.

This study is categorized as a regulatory post-marketing surveillance in Japan, and it is a local prospective and observational study of patients who have received Xarelto for SPAF.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
741
Inclusion Criteria
  • Patients treated by Warfarin for their atrial fibrillation for at least two months at the time of the study initiation.
  • Rivaroxaban naïve patients
  • Patients 20 years old or older.
  • Patients who agree to sign the inform consent
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Exclusion Criteria
  • Patients who are contraindicated by product label
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Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Group 1Rivaroxaban (Xarelto_ BAY59-7939)Patients treated with Xarelto under practical manner for SPAF.
Primary Outcome Measures
NameTimeMethod
Incidence of events of strokeUp to 6 months
Incidence of events of non-central nervous system embolismUp to 6 months
Improvement of treatment satisfaction (Evaluated through ACTS and TSQM questionnaires)Up to 6 months
Incidence of ADRs and serious AEs (especially for hemorrhagic events, and liver disfunction with increase of liver-function-relating enzymes including bilirubin)Up to 6 months
Secondary Outcome Measures
NameTimeMethod
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