Quadratus Lumborum Block Reduced Postpartum Uterine Pain After Virginal Childbirth

Not Applicable

Completed

• Conditions: Postpartum Cramping; Vaginal Delivery; Quadratus Lumborum Nerve Block
• Interventions: Procedure: quadratus lumborum nerve block (ropivacaine ); Procedure: quadratus lumborum nerve block (normal saline)

• Registration Number: NCT05371015
• Lead Sponsor: Chang Gung Memorial Hospital

Brief Summary

With the continuous advancement of ultrasonic technology, nerve block in which drugs are injected into the periphery of the target nerve through ultrasonic guidance has become the mainstream method for postoperative pain control. The quadratus lumborum nerve block has been effectively and safely used in abdominal surgery (such as laparotomy, caesarean section, etc.), effectively reducing postoperative wounds and visceral pain. There is no research on the use of quadratus lumborum nerve block to control the pain of natural postpartum uterine contractions in the current literature, so the purpose of this experiment is to explore whether the quadratus lumborum nerve block can effectively reduce the pain of uterine contractions after vaginal delivery.

Detailed Description

Not available

Study Timeline

• Status Verified: 2022-02
• Study First Submitted: 2022-04-05
• Study First Submitted QC: 2022-05-11
• Study Start: 2022-05-12
• Study First Posted: 2022-05-12
• Primary Completion: 2022-08-31
• Study Completion: 2022-08-31
• Last Update Submitted: 2024-03-12
• Last Update Posted: 2024-03-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 66

Inclusion Criteria

• Females over twenty years of age
• Maternal vaginal delivery
• Postpartum moderate to severe pain with uterine contractions (Numerical Pain Scale (NRS) ≥ 4 points) after delivery.
• Subject's consent signed by the subject

Exclusion Criteria

• Severe coagulation abnormalities (PLT<100000、INR>1.2、PT>13)
• Infection of the epidermis at the anticipated relevant site of injection
• Allergy to local anesthetics
• Allergy to or abuse of pain control medications
• Episiotomy is more painful than uterine contractions
• Inability to cooperate with associated pain assessment
• Body Mass Index (BMI) ≧ 35 kg/m2

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
quadratus lumborum nerve block group with injection of local anesthetic (Ropivacaine)	quadratus lumborum nerve block (ropivacaine )	The subjects would have quadratus lumborum nerve block group with injection of local anesthetic (Ropivacaine) after vaginal delivery.
quadratus lumborum nerve block with normal saline	quadratus lumborum nerve block (normal saline)	The subjects would have quadratus lumborum nerve block with normal saline after vaginal delivery.

Primary Outcome Measures

Name	Time	Method
Pain associated with uterine contractions	48 hours after intervention	Grading with Numerical Pain Scale \[0 (no pain at all) to 10 (worst imaginable pain)\] and Visual Analogue Scale \[mark a position between 0 (no pain at all) to 10 (worst imaginable pain)\]

Trial Locations

Locations (1)

Chang Gung Memorial Hospital (Linkou); 🇨🇳 Taoyuan City, Taiwan