The effect of Moringa oleifera leaves on platelet aggregation in healthy adults and hypertensive patients.
Phase 2
- Conditions
- Platelet dysfunctions, endothelial dysfunction, and high blood pressure in healthy adults and hypertensive patients.thromboembolism, hypertension, healthy population and patients with hypertension
- Registration Number
- TCTR20221027002
- Lead Sponsor
- Faculty of Medicine Ramathibodi Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
1. age 40-59 years
2. Systolic blood pressure < 140 mmHg and diastolic blood pressure < 90 mmHg for healthy population group
3. Systolic blood pressure 140-159 mmHg and diastolic blood pressure 90-99 mmHg for hypertensive group
Exclusion Criteria
1. smoking
2. pregnancy
3. medication or herbal use that affects platelet function
4. medical conditions or underlying diseases that affects platelet function
5. underlying diseases: cardiovascular diseases, chronic lung diseases, chronic liver diseases, chronic kidney diseases, and cancer, etc.
6. participants' voluntary withdrawal of consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Platelet aggregation within 4 hours Flow cytometry
- Secondary Outcome Measures
Name Time Method endothelial function within 4 hours chemiluminescence