Autologous Fat Grafting With PRP (Platelet Rich Plasma) to Anophthalmic Sockets
- Conditions
- Orbital Atrophy
- Interventions
- Procedure: autologous fat grafting with PRP to anophthalmic orbits
- Registration Number
- NCT01712555
- Lead Sponsor
- Fox, Donald Munro, M.D., P.C.
- Brief Summary
After people lose an eye, for whatever reason, they often experience fat atrophy of the tissues in the orbit. This leads to a sunken appearance that is often not correctable by a cosmetic shell prosthesis. Current techniques to correct this deformity are inadequate/ invasive. Injection of various gels (Restylane, Radiesse) are temporary had have their own disadvantages. This study seeks to demonstrate an improvement in the retention of injected autologous fat by mixing in autologous PRP (platelet rich plasma).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 5
anophthalmos, orbital atrophy -
poor anesthesia risk, people outside a 100 mile radius of New York City
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description fat grafting with PRP to anophthalmic orbits autologous fat grafting with PRP to anophthalmic orbits There is only one arm to this study. People with orbital atrophy and loss of an eye are to be injected with autologous fat mixed with autologous PRP (platelet rich plasma) and observed for at least one year for evidence of retention of the injected fat
- Primary Outcome Measures
Name Time Method Improved retention of autologous fat injected into anophthalmic sockets 1-5 yrs Non contrast MRIs of the orbits are obtained before, immediately after, and one year after injection of autologous fat mixed with autologous PRP (platelet rich plasma)
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
New York Eye and Ear Infirmary
🇺🇸New York, New York, United States