Skip to main content
MedPathMedPath Home
Clinical Trials/DRKS00033526
DRKS00033526
Recruiting
Not Applicable

Genetic variants of sex hormone receptors in patients with atrial fibrillation - GENE-AF

Klinikum Bielefeld Mitte0 sites40 target enrollmentJanuary 31, 2024
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
ConditionsI48Atrial fibrillation and flutter

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
I48
Sponsor
Klinikum Bielefeld Mitte
Enrollment
40
Status
Recruiting
Last Updated
last year
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
January 31, 2024
End Date
TBD
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Sponsor
Klinikum Bielefeld Mitte

Eligibility Criteria

Inclusion Criteria

  • •Patients with atrial fibrillation (ICD\-10 code: I48\.0 or I48\.1\) \> 18 years of age
  • •\- Postmenopausal status in women (last menstrual period \> 12 months ago). Premenopausal women would experience excessive hormonal fluctuations due to their menstrual cycle.
  • •\- Ability to give consent and sufficient knowledge of German

Exclusion Criteria

  • •\- Obesity \= size II (BMI \= 35kg/m2\)
  • •\- Manifest hyperthyroidism (TSH \< 0\.25 µIU/ml)
  • •\- Harmful alcohol use according to ICD10/WHO definition
  • •\- The following valve conditions: mitral valve stenosis, moderate/high\-grade aortic valve stenosis, moderate/high\-grade mitral valve insufficiency
  • •\- Postoperative status (operation \< 10 d)
  • •\- Sepsis according to WHO definition
  • •\- Acute or chronic infections (CRP \> 15 mg/dl)
  • •\- Indications of CHD (corresponding symptoms, echocardiographic or ECG morphological abnormalities) or already diagnosed CHD
  • •\- Hypokalemia (K\+ \< 3\.0 mmol/l)
  • •\- Acute or chronic right heart strain (systolic pulmonary artery pressure (sPAP) \= 36 mmHg in transthoracic echocardiography) (e.g. pulmonary artery embolism or COPD)

Outcomes

Primary Outcomes

Not specified

Similar Trials

Completed
Not Applicable
The expression of the sex steroids receptor and serum sex steroids status in uterine fibroids, endometriosis, and uterine adnomyosisuterine fibroma, endometriosis, uterine adenomyosis
JPRN-UMIN000014770Dept of Obstetrics and Gynececology, Osaka medical college.150
Not yet recruiting
Not Applicable
Prevalence of FSH receptor polymorphism in young women undergoing in vitro fertilizatio
CTRI/2020/08/027134Christian Medical College Vellore
Completed
Not Applicable
Sex hormones, sex chromosomes, and sexual differentiation of the braiSexual differentiation of the braindisorder of sex developmenttesticular feminization1003860810040480
NL-OMON36349etherlands Institute for Neuroscience80
Completed
Not Applicable
Hormonal therapy resistant estorgen receptor positive metastatic breast cancer cohort studyBreast cancer
JPRN-UMIN000019556General Incorporated Association of CSPOR-BC200
Active, not recruiting
Not Applicable
Significance of the FSH receptor polymorphism p.N680S for the efficacy of FSH therapy of idiopathic male infertility: a pharmacogenetic approach. - NDIdiopathic male infertilityMedDRA version: 9.1Level: HLGTClassification code 10014701MedDRA version: 9.1Level: LLTClassification code 10021011
EUCTR2010-020240-35-ITAZIENDA OSPEDALIERA POLICLINICO DI MODENA100