Promotion and Application of a New Three-level Etiological Diagnosis Strategy for Fever Clinics in Respiratory Infectious Diseases
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,255
- 试验地点
- 12
- 主要终点
- the detectioin rate of pathogenic microorganism in each step
研究概览
简要总结
Relying on fever clinics, this project evaluates the clinical diagnostic efficiency of the three-level pathogen diagnostic system, monitors changes in respiratory pathogens, and realizes real-time monitoring and early warning of acute respiratory infectious diseases in Shanghai.
详细描述
This study mainly includes subjects who enter the outpatient and emergency departments, fever clinics, and wards of each center from December 2022. According to the clinical manifestations and epidemiological information of the patients, different step-by-step detection methods will be adopted to optimize the allocation of clinical resources and improve the quality of life. This study aims to improve pathogen diagnosis efficiency and achieve regional respiratory early warning.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 12 Years 至 100 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Acute onset within one week;
- •18-70 years old;
- •Present with pneumonia (present with pulmonary signs or radiological changes) or influenza-like illness (including the following symptoms: sudden onset of fever (>38 ℃),plus cough and/or other respiratory symptoms such as shortness of breath plus one or more systemic symptoms (fatigue, headache ect.))
排除标准
- •Unable to collect nasal/nasopharyngeal swab/wash/aspirate due to structural disorder or mental problem.
- •Patients with psycological problem or unconsciousness who cannot tell the disease history and cooperate with medical examinations;
结局指标
主要结局
the detectioin rate of pathogenic microorganism in each step
时间窗: 48 hours
the detectioin rate of pathogenic microorganism in each step
次要结局
- rate of critical illness(48 hours)
- hospitalization rate(48 hours)
研究者
Wen-hong Zhang
Director of Division of Infectious Diseases
Huashan Hospital