Identifying Perceived Barriers and Facilitators to Inform the Development of a Liver Transplantation Prehabilitation Intervention
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 114
- 试验地点
- 1
- 主要终点
- Liver frailty index (LFI) score
研究概览
简要总结
The purpose of this study is to formally identify patient and caregiver perceived needs, barriers, and facilitators to inform the development of a home-based multimodal prehabilitation program for potential LT candidates.
详细描述
After being informed about the study and potential risks, all participants (patients and caregivers) giving written informed consent will be invited to participate in one of three research activities: interviews (n=10), nominal group technique meetings (n=64), or card-sorting and rating survey (n=40).
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 74 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Liver transplant (LT) candidates are:
- •Adult ESLD patients (age=19-74 years) who are assigned to the LT waitlist
- •English-speaking
- •No contraindication to moderate intensity physical activities
- •Physician clearance for participation in moderate intensity physical activities
- •No history of dementia or organic brain syndrome
- •Caregivers:
- •Adult (age≥ 19 years)
- •English-speaking
- •Provide direct care to LT candidates
排除标准
- •Inability to communicate verbally in English
- •Documentation of cognitive deficits
结局指标
主要结局
Liver frailty index (LFI) score
时间窗: From baseline through 3 months
Change from baseline in liver frailty index score at 3 months; the higher LFI scores indicate a higher degree of frailty. LFI\<3.2: robust, LFI=3.2-4.4: prefrail, LFI\>=4.5: Frail.
Caregiver burden measured using Zarit Burden Interview short form (ZBI-12)
时间窗: From baseline through 3 months
Change from baseline in the total ZBI-12 scores at 3 months. The total ZBI-12 score is the summation of 12 items, ranging from 0 to 48; the higher scores indicate higher burden (0-10:no to mild burden; 10-20: mild to moderate burden), and \>20: high burden.
次要结局
未报告次要终点
研究者
Haiyan Qu
Associate Professor
University of Alabama at Birmingham