Seizures in Infants Hospitalized in Pediatric Intensive Care Unit for Bronchiolitis

Completed

• Conditions: Hyponatremia; Seizures; Bronchiolitis
• Interventions: Other: Incidence, management and risk factors of seizure

• Registration Number: NCT04022486
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

Bronchiolitis is the leading cause of pediatric intensive care unit admission in infants. Seizures during bronchiolitis may be a neurological complication of respiratory viruses but also of the treatments. The investigating team's hypothesis is that the incidence of seizures is not so so uncommon in infants hospitalized in the pediatric intensive care unit for severe bronchiolitis.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-04-01
• Primary Completion: 2018-08-01
• Study Completion: 2019-05-01
• Status Verified: 2019-07
• Study First Submitted: 2019-07-15
• Study First Submitted QC: 2019-07-15
• Last Update Submitted: 2019-07-15
• Study First Posted: 2019-07-17
• Last Update Posted: 2019-07-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 805

Inclusion Criteria

• age < 90 days
• hospitalization from January 1st, 2010 to April 30th, 2018 in the Pediatric Intensive Care Unit (PICU) of pediatric hospital in Lyon
• with bronchiolitis (clinical diagnosis according to American Academy of Pediatrics)

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Exclusion Criteria

• neurological history that may explain the occurrence of seizures
• significant congenital heart disease

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Children admitted in the PICU for severe bronchiolitis	Incidence, management and risk factors of seizure	Children admitted in the Pediatric Intensive Care Unit (PICU) for severe bronchiolitis between January 1st, 2010 and April 30th, 2018

Primary Outcome Measures

Name	Time	Method
: Incidence of seizure during bronchiolitis (before or during hospitalization in the pediatric intensive care unit)	Day 1	Clinical or infra-clinical (diagnosed on Electroencephalography, EEG) seizure, simple or status epilepticus

Trial Locations

Locations (1)

Hôpital Femme Mère Enfant; 🇫🇷 Bron, France