Chemotherapy Followed by Surgery and Neoadjuvant Hemothoracic Intensity Modified Radiation Therapy (IMRT) for Patients With Malignant Pleural Mesothelioma
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Mesothelioma
- Sponsor
- Mayo Clinic
- Enrollment
- 8
- Locations
- 1
- Primary Endpoint
- Overall Survival (OS)
- Status
- Terminated
- Last Updated
- last year
Overview
Brief Summary
The purpose of this study is to determine the response rate and overall survival in patients that have been diagnosed with mesothelioma and will undergo chemotherapy, surgery and intensity modified radiation therapy (IMRT) as part of their standard of care.
Detailed Description
The investigators will consent patients that have been diagnosed with mesothelioma and will undergo chemotherapy followed by surgery and then IMRT as their standard of care. The investigators will collect data from past and future medical records as well as data regarding their health status for their lifetime by reviewing life status, treatment status and CT scans.
Investigators
Dennis Wigle
Principal Investigator
Mayo Clinic
Eligibility Criteria
Inclusion Criteria
- •Subject provides informed consent
- •Subject is \>18 years of age
- •Subject is deemed competent for making medical decisions
- •Subject is scheduled to undergo chemotherapy followed by surgery and then IMRT
- •Subject is a surgical candidate
- •A negative pregnancy test is required in women of child-bearing potential, as standard of care.
Exclusion Criteria
- •Subject is \<18 years old.
Outcomes
Primary Outcomes
Overall Survival (OS)
Time Frame: 2 years
OS is defined as the length of time from study enrollment to death by any cause. Survival status of patients will be monitored every 6 months
Secondary Outcomes
- Progression free survival (PFS) as evidenced by CT scan review(2 years)