Chemotherapy Followed by Surgery and Neoadjuvant Hemothoracic Intensity Modified Radiation Therapy (IMRT) for Patients With Malignant Pleural Mesothelioma
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- Mayo Clinic
- 入组人数
- 8
- 试验地点
- 1
- 主要终点
- Overall Survival (OS)
研究概览
简要总结
The purpose of this study is to determine the response rate and overall survival in patients that have been diagnosed with mesothelioma and will undergo chemotherapy, surgery and intensity modified radiation therapy (IMRT) as part of their standard of care.
详细描述
The investigators will consent patients that have been diagnosed with mesothelioma and will undergo chemotherapy followed by surgery and then IMRT as their standard of care. The investigators will collect data from past and future medical records as well as data regarding their health status for their lifetime by reviewing life status, treatment status and CT scans.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subject provides informed consent
- •Subject is >18 years of age
- •Subject is deemed competent for making medical decisions
- •Subject is scheduled to undergo chemotherapy followed by surgery and then IMRT
- •Subject is a surgical candidate
- •A negative pregnancy test is required in women of child-bearing potential, as standard of care.
排除标准
- •Subject is <18 years old.
结局指标
主要结局
Overall Survival (OS)
时间窗: 2 years
OS is defined as the length of time from study enrollment to death by any cause. Survival status of patients will be monitored every 6 months
次要结局
- Progression free survival (PFS) as evidenced by CT scan review(2 years)