EIS-GO: Early Identification of Steroid non-response in moderate severe active Graves* Orbitopathy, a prospective study

• Conditions: Graves' orbitopathy; 10015917

• Registration Number: NL-OMON51784
• Lead Sponsor: Oogziekenhuis Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 9 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

Active, moderate-severe GO.

Exclusion Criteria

Treatment with steroids or other immunomodulating drugs in the past 3 months.
Contra-indication for intravenous methyl prednisone (IVMP).

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>In vitro steroid sensitivity assay and clinical response to treatment with<br /><br>intravenous steroids.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary endpoints for clinical steroid respons (see protocol 8.1.2)<br /><br>Quality of Life questionnaires</p><br>