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Effects of probiotic on nonalcolic steatohepatitis

Not Applicable
Conditions
onalcoholic steatohepatitis.
Inflammatory liver disease, unspecified Hepatitis NOS
Registration Number
IRCT201204049376N1
Lead Sponsor
Isfahan University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
63
Inclusion Criteria

patients admitted to Al Zahra hospital over 18 years, who have NASH confirmed by biopsy.
Exclusion criteria: any participant who will take antibiotics for any indication for more than 1 week during the study period or before recruitment to the study; loosing more than 10% of baseline body weight during the study period; autoimmune hepatitis; Wilson's disease; HBV/HCV/HIV/EBV/CMV infection; pregnancy and lactation

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Alanine transaminase (ALT). Timepoint: Before and after treatment. Method of measurement: Blood test.;Aspartate aminotransferse (AST). Timepoint: before and after treatment. Method of measurement: blood test AST.;Ultrasound Grade of NASH. Timepoint: before and after treatment. Method of measurement: ultrasound.
Secondary Outcome Measures
NameTimeMethod
Fasting blood suger (FBS). Timepoint: before and after treatment. Method of measurement: blood test.;Chlosterol. Timepoint: befoer and after treatment. Method of measurement: blood test.;Triglyceride. Timepoint: before and after treatment. Method of measurement: blood test.;Body mass index (BMI). Timepoint: before and after treatment. Method of measurement: measure weight and height.
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