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临床试验/NCT05549349
NCT05549349终止不适用

ANGH Prospective Cohort of Mild and Severe Acute Biliary Pancreatitis

Julia TRAVAGLI1 个研究点 分布在 1 个国家目标入组 2,000 人开始时间: 2022年10月10日最近更新:
适应症

试验速览

阶段
不适用
状态
终止
发起方
入组人数
2,000
试验地点
1
主要终点
biliary events

研究概览

简要总结

The main objective of this work is to evaluate the recurrence of biliary episodes before cholecystectomy (hepatic colic, lithiasic migration, cholangitis, cholecystitis, pancreatitis, necrosis infections) in patients with acute biliary pancreatitis of any severity depending on the type of nutrition (oral, enteral or parenteral).

详细描述

Acute pancreatitis (AP) is one of the frequent causes of hospitalization in gastroenterology with an annual incidence of 13-45 cases per 100,000 patients. If we refer to the data in the white paper, hospitalizations for abdominal emergencies, such as PA, take place in at least 60% of cases in General Hospital Centers (CHG). Among these AP, approximately 40% of AP are secondary to a biliary lithiasis pathology. The main modalities of the initial management of AP have been the subject of several national and international recommendations and consensuses. Although it is well accepted that early refeeding during the first 48 hours reduces the appearance of a systemic inflammatory response syndrome (SIRS) or a collection infection, the feeding methods in the event of pancreatitis Acute biliary (ABP) during the acute phase using the oral route if it is tolerated or the enteral route by nasogastric tube before cholecystectomy remains debated.

Thus, in case of delayed cholecystectomy after AP, there is no consensus on the feeding methods after the acute phase (oral or enteral) until cholecystectomy nor on the benefit of a prophylactic endoscopic sphincterotomy in the absence of cholangitis.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adult over 18 years old
  • Affiliated to a social security scheme.
  • Patients with acute biliary pancreatitis

排除标准

  • Patients with chronic pancreatitis
  • Patients with a previous cholecystectomy
  • Patients under guardianship, curatorship or legal protection

结局指标

主要结局

biliary events

时间窗: 3 month

Assess the recurrence of biliary events before cholecystectomy

次要结局

未报告次要终点

研究者

发起方
Julia TRAVAGLI
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Julia TRAVAGLI

PhD

Poissy-Saint Germain Hospital

研究点 (1)

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