Retrospective Study About Primary Biliary Cholangitis During January 2001 to July 2016 at West China Hospital

Completed

• Conditions: Cholangitis; Liver Cirrhosis, Biliary; Cholestasis; Liver Diseases; Liver Cirrhosis; Bile Duct Diseases

• Registration Number: NCT02917408
• Lead Sponsor: Xiaoli Fan

Brief Summary

Retrospective study of all patients diagnosed with primary biliary cholangitis during January 2001 to July 2016 at West China Hospital by review of medical records. The following variables will be retrospectively studied: age, sex, first symptoms, clinical characteristics, pathology, treatment, stage, complications of cirrhosis, other autoimmune diseases and long-term outcome.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-09
• Study First Submitted: 2016-09-06
• Study First Submitted QC: 2016-09-26
• Study First Posted: 2016-09-28
• Primary Completion: 2017-01
• Study Completion: 2017-01
• Status Verified: 2020-11
• Last Update Submitted: 2020-11-07
• Last Update Posted: 2020-11-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 769

Inclusion Criteria

• Newly diagnosis of PBC at West China Hospital during January 2001 to July 2016.

Exclusion Criteria

• Simultaneously diagnosed of autoimmune hepatitis or primary sclerosing cholangitis.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Description of demographics, management patterns (clinical and diagnostic), comorbidities of PBC patients at diagnosis during the past 16 years.	Up to 16 years.

Secondary Outcome Measures

Name	Time	Method
Evaluation of adverse outcome free survival of the PBC cohort during the 16 years.	Up to 16 years.

Trial Locations

Locations (1)

West China Hospital; 🇨🇳 Chengdu, Sichuan, China