Acetaminophen in the treatment of schizophrenia
Not Applicable
- Conditions
- schizophrenia.schizophrenia
- Registration Number
- IRCT201410251556N67
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Inclusion Criteria:1-Diagnosis of Schizophrenia based on DSM-5 criteria;2- Minimum Score of 60 on Positive and Negative Scale 3- Age between 18-55; 4- chronic Schizophrenia- duration of the disorder more than 2 years; ; 6-Minimum score of 20 in negative suscale
Exclusion Criteria
1-any other major mental disorder based on DSM-5; 2-Any serious medical or neurological problem; 3- IQ less than 70;4- Substance dependence during the last 6 months(except for nicotine and caffeine) 5-receiving oral antipsychotic medications during the last week or receiving any depot antipsychotic medication during the last month; ;6-receiving ECT during the last 14 days,7-hepatic and renal disease; 7- history of abnormal bleeding
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of schizophrenia. Timepoint: Baseline and weeks 2-4-8 after beginig of treatment. Method of measurement: by Positive and Negative Symptoms Scale(PANSS).
- Secondary Outcome Measures
Name Time Method Extrapyramidal side effects. Timepoint: Baseline and weeks 2-4-6-8 after beginig of treatment. Method of measurement: by Extrapyramidal Symptoms Rating Scale.