The effect of acetaminophen on propofol injection pai

Phase 3

• Conditions: ocal Pain due to intravenous injection of propofol.; Pain in unspecified hand; M79.643

• Registration Number: IRCT20210511051268N1
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 May 2021

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

All patients for whom propofol is used as an induction of anesthesia

Exclusion Criteria

Weight less than 50 kg
Chronic pain in any area of ??the body
High blood pressure
Cardiovascular disease
Cerebrovascular disease
Difficulty communicating (even if there is a marked drop in level of consciousness with the initial injection dose)
Cirrhosis
Abnormal liver function test results (AST and ALT more than twice normal)
Kidney failure or creatinine clearance greater than 1.2
Allergy to acetaminophen
Allergy to propofol
Patients in whom propofol is not used to induce anesthesia
Those who do not have a venous catheter in the back of the hand
Those whose catheter size is not 20G
those for whom we have to use rapid sequence induction for their anesthesia

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
11-point verbal numerical rating score (VNRS) for pain caused by propofol injection. Timepoint: Measuring the amount of pain right after injecting a quarter of the induction dose. Method of measurement: 11-Point Verbal Numerical Ranking (VNRS).