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Clinical Trials/NCT06186713
NCT06186713
Completed
Not Applicable

Pulmonary Hypertension on Prognosis of Acute Myocardial Infarction Patients With Reduced Left Ventricular Function (STIMULATE): A Single-center, Retrospective Cohort Study

First Affiliated Hospital Xi'an Jiaotong University1 site in 1 country4,784 target enrollmentMarch 30, 2023
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ConditionsAcute Myocardial InfarctionPulmonary Hypertension

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Acute Myocardial Infarction
Sponsor
First Affiliated Hospital Xi'an Jiaotong University
Enrollment
4784
Locations
1
Primary Endpoint
The incidence of all-cause death
Status
Completed
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

Pulmonary hypertension (PH) has a negative effect on acute myocardial infarction (AMI) patients and appears to be closely associated with reduced left ventricular function. However, its impact on AMI patients with reduced left ventricular function remains unclear. This retrospective study included AMI patients with reduced left ventricular function to investigate the prognostic value of PH in this specific type of patient. Meanwhile, a nomogram would be established basing on the identified independent risk factors, hoping to provide a novel risk stratification for them.

Registry
clinicaltrials.gov
Start Date
March 30, 2023
End Date
August 1, 2023
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • •The patients who were hospitalized for AMI with reduced left ventricular function at the First Affiliated Hospital of Jiaotong University from January 2018 to January 2022.

Exclusion Criteria

  • •Myocardial infarction complicated by cardiac rupture.
  • •Significant pre-existing heart failure.
  • •Other comorbidities such as malignancy that may significantly affect prognosis.
  • •Incomplete clinical data.

Outcomes

Primary Outcomes

The incidence of all-cause death

Time Frame: 1-year after the AMI.

All-cause death will be determined by clinical records or phone calls with patients and their family.

Study Sites (1)

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