Molecular perspective on the effect of Yoga on Chronic Kidney Disease and Health Related Quality of Life - A Randomized Control Trial

Not Applicable

• Conditions: Health Condition 1: null- Chronic Kidney Disease

• Registration Number: CTRI/2017/09/009846
• Lead Sponsor: Self funded

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Patients identified with CKD Stages 3 & 4 [15 < GFR < 60 mL/min per 1·73 m²]

Patients identified with nephropathy (Diabetics or Hypertensive nephropathy)

Age ranging from 35 to 60 from both gender

Willingness to participate in a 12 - week yoga program

Exclusion Criteria

Persons identified / diagnosed with;

Genetic kidney diseases,

Inflammatory or Infectious type nephropathy (Glomerulonephritis, SLE, M - Nephropathy / Pyelonephritis, PIGN, etc)

Type 1 Diabetes Mellitus, Uncontrolled Diabetes and Hypertension, Morbid obesity,

Acute Kidney Injury (AKI)

Persons identified with renal carcinoma, polycystic kidney disease, UTI, Kidney stones

Severe cognitive decline, immobilized or severe mobility restriction

Persons identified with any other serious problem that can confound the outcome data

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
TGF beta1 <br/ ><br>Serum Creatinine <br/ ><br>Serum Cystatin C <br/ ><br>Urinary Albumin and Creatinine <br/ ><br>Oxidized Low-density Lipoprotein <br/ ><br>Malondialdehyde <br/ ><br>Advanced Oxidative Protein Products <br/ ><br>Superoxide Dismutase Glutathione peroxidase <br/ ><br>Catalase <br/ ><br>HRQoL measures <br/ ><br>Glomerular Filtration Rate Urinary Albumin Creatinine Ratio <br/ ><br>Timepoint: Before and after the intervention

Secondary Outcome Measures

Name	Time	Method
Fasting Blood Sugar (FBS) <br/ ><br>Post Prandial Blood Sugar (PPBS) <br/ ><br>HbA1C: Glycated Haemoglobin <br/ ><br>Blood Pressure: (Systolic / Diastolic) <br/ ><br>Anthropometrics <br/ ><br>Timepoint: Before and after the intervention